Cargando…

Cellular and metabolic mechanisms of nutrient actions in immune function

Various nutrients can change cell structure, cellular metabolism, and cell function which is particularly important for cells of the immune system as nutrient availability is associated with the activation and function of diverse immune subsets. The most important nutrients for immune cell function...

Descripción completa

Detalles Bibliográficos
Autor principal: Newsholme, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223523/
https://www.ncbi.nlm.nih.gov/pubmed/34168118
http://dx.doi.org/10.1038/s41387-021-00162-3
_version_ 1783711711024381952
author Newsholme, Philip
author_facet Newsholme, Philip
author_sort Newsholme, Philip
collection PubMed
description Various nutrients can change cell structure, cellular metabolism, and cell function which is particularly important for cells of the immune system as nutrient availability is associated with the activation and function of diverse immune subsets. The most important nutrients for immune cell function and fate appear to be glucose, amino acids, fatty acids, and vitamin D. This perspective will describe recently published information describing the mechanism of action of prominent nutritional intervention agents where evidence exists as to their action and potency.
format Online
Article
Text
id pubmed-8223523
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-82235232021-06-25 Cellular and metabolic mechanisms of nutrient actions in immune function Newsholme, Philip Nutr Diabetes Mini Review Various nutrients can change cell structure, cellular metabolism, and cell function which is particularly important for cells of the immune system as nutrient availability is associated with the activation and function of diverse immune subsets. The most important nutrients for immune cell function and fate appear to be glucose, amino acids, fatty acids, and vitamin D. This perspective will describe recently published information describing the mechanism of action of prominent nutritional intervention agents where evidence exists as to their action and potency. Nature Publishing Group UK 2021-06-23 /pmc/articles/PMC8223523/ /pubmed/34168118 http://dx.doi.org/10.1038/s41387-021-00162-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Mini Review
Newsholme, Philip
Cellular and metabolic mechanisms of nutrient actions in immune function
title Cellular and metabolic mechanisms of nutrient actions in immune function
title_full Cellular and metabolic mechanisms of nutrient actions in immune function
title_fullStr Cellular and metabolic mechanisms of nutrient actions in immune function
title_full_unstemmed Cellular and metabolic mechanisms of nutrient actions in immune function
title_short Cellular and metabolic mechanisms of nutrient actions in immune function
title_sort cellular and metabolic mechanisms of nutrient actions in immune function
topic Mini Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223523/
https://www.ncbi.nlm.nih.gov/pubmed/34168118
http://dx.doi.org/10.1038/s41387-021-00162-3
work_keys_str_mv AT newsholmephilip cellularandmetabolicmechanismsofnutrientactionsinimmunefunction