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Meigs’ syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions: A case report
BACKGROUND: Meigs’ syndrome is regarded as a benign ovarian tumor accompanied by pleural effusion and ascites, both of which resolve after removal of the tumor. Patients often seek treatment in the Department of Respiratory and Critical Care Medicine or other internal medicine departments due to sym...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Baishideng Publishing Group Inc
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223816/ https://www.ncbi.nlm.nih.gov/pubmed/34222440 http://dx.doi.org/10.12998/wjcc.v9.i18.4734 |
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author | Wu, Xiao-Juan Xia, Hang-Biao Jia, Bao-Lin Yan, Gao-Wu Luo, Wen Zhao, Yong Luo, Xiao-Bin |
author_facet | Wu, Xiao-Juan Xia, Hang-Biao Jia, Bao-Lin Yan, Gao-Wu Luo, Wen Zhao, Yong Luo, Xiao-Bin |
author_sort | Wu, Xiao-Juan |
collection | PubMed |
description | BACKGROUND: Meigs’ syndrome is regarded as a benign ovarian tumor accompanied by pleural effusion and ascites, both of which resolve after removal of the tumor. Patients often seek treatment in the Department of Respiratory and Critical Care Medicine or other internal medicine departments due to symptoms caused by ascites or hydrothorax. Here, we report a rare case of Meigs' syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions. CASE SUMMARY: A 52-year-old women was admitted to the Department of Respiratory and Critical Care Medicine due to coughing and expectoration accompanied with shortness of breath. Chest X-ray and chest computed tomography showed a modest volume of pleural fluid with pleural thickening in the right lung. The carbohydrate antigen 125 (CA125) concentration was 150.8 U/mL (normal, 0-35 U/mL) and no tumor cells were observed in pleural fluid. Nodules and a neoplasm with a fish meat-like appearance in the parietal pleura and nodules with a ‘string of beads’-like appearance in the diaphragm were found by thoracoscopic examination. Furthermore, pelvic magnetic resonance revealed a pelvic mass measuring about 11.6 cm × 10.0 cm × 12.4 cm with heterogeneous signal intensity and multiple hypointense separations. Total abdominal hysterectomy, bilateral adnexectomy, and separation of pelvic adhesion were performed under general anesthesia. The pathology results showed granulosa cell tumor. At the 2-mo follow-up after the surgery, the hydrothorax subsided, and the CA125 level returned to normal. CONCLUSION: For postmenopausal women with unexplained hydrothorax and elevated CA125, in addition to being suspected of having gynecological malignancy, Meigs’ syndrome should be considered. |
format | Online Article Text |
id | pubmed-8223816 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-82238162021-07-02 Meigs’ syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions: A case report Wu, Xiao-Juan Xia, Hang-Biao Jia, Bao-Lin Yan, Gao-Wu Luo, Wen Zhao, Yong Luo, Xiao-Bin World J Clin Cases Case Report BACKGROUND: Meigs’ syndrome is regarded as a benign ovarian tumor accompanied by pleural effusion and ascites, both of which resolve after removal of the tumor. Patients often seek treatment in the Department of Respiratory and Critical Care Medicine or other internal medicine departments due to symptoms caused by ascites or hydrothorax. Here, we report a rare case of Meigs' syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions. CASE SUMMARY: A 52-year-old women was admitted to the Department of Respiratory and Critical Care Medicine due to coughing and expectoration accompanied with shortness of breath. Chest X-ray and chest computed tomography showed a modest volume of pleural fluid with pleural thickening in the right lung. The carbohydrate antigen 125 (CA125) concentration was 150.8 U/mL (normal, 0-35 U/mL) and no tumor cells were observed in pleural fluid. Nodules and a neoplasm with a fish meat-like appearance in the parietal pleura and nodules with a ‘string of beads’-like appearance in the diaphragm were found by thoracoscopic examination. Furthermore, pelvic magnetic resonance revealed a pelvic mass measuring about 11.6 cm × 10.0 cm × 12.4 cm with heterogeneous signal intensity and multiple hypointense separations. Total abdominal hysterectomy, bilateral adnexectomy, and separation of pelvic adhesion were performed under general anesthesia. The pathology results showed granulosa cell tumor. At the 2-mo follow-up after the surgery, the hydrothorax subsided, and the CA125 level returned to normal. CONCLUSION: For postmenopausal women with unexplained hydrothorax and elevated CA125, in addition to being suspected of having gynecological malignancy, Meigs’ syndrome should be considered. Baishideng Publishing Group Inc 2021-06-26 2021-06-26 /pmc/articles/PMC8223816/ /pubmed/34222440 http://dx.doi.org/10.12998/wjcc.v9.i18.4734 Text en ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Case Report Wu, Xiao-Juan Xia, Hang-Biao Jia, Bao-Lin Yan, Gao-Wu Luo, Wen Zhao, Yong Luo, Xiao-Bin Meigs’ syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions: A case report |
title | Meigs’ syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions: A case report |
title_full | Meigs’ syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions: A case report |
title_fullStr | Meigs’ syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions: A case report |
title_full_unstemmed | Meigs’ syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions: A case report |
title_short | Meigs’ syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions: A case report |
title_sort | meigs’ syndrome caused by granulosa cell tumor accompanied with intrathoracic lesions: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223816/ https://www.ncbi.nlm.nih.gov/pubmed/34222440 http://dx.doi.org/10.12998/wjcc.v9.i18.4734 |
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