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Lytic Infection with Murine Gammaherpesvirus 68 Activates Host and Viral RNA Polymerase III Promoters and Enhances Noncoding RNA Expression

RNA polymerase III (pol III) transcribes multiple noncoding RNAs (ncRNAs) that are essential for cellular function. Pol III-dependent transcription is also engaged during certain viral infections, including those of the gammaherpesviruses (γHVs), where pol III-dependent viral ncRNAs promote pathogen...

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Detalles Bibliográficos
Autores principales: Knox, Ashley N., Mueller, Alice, Medina, Eva M., Clambey, Eric T., van Dyk, Linda F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223928/
https://www.ncbi.nlm.nih.gov/pubmed/33910955
http://dx.doi.org/10.1128/JVI.00079-21