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Anti-Cancer and Immunomodulatory Activity of a Polyethylene Glycol-Betulinic Acid Conjugate on Pancreatic Cancer Cells

Drug delivery systems involving polymer therapeutics enhance drug potency by improved solubility and specificity and may assist in circumventing chemoresistance in pancreatic cancer (PC). We compared the effectiveness of the naturally occurring drug, betulinic acid (BA), alone and in a polymer conju...

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Detalles Bibliográficos
Autores principales: Fru, Pascaline Nanga, Nweke, Ekene Emmanuel, Mthimkhulu, Nompumelelo, Mvango, Sindisiwe, Nel, Marietha, Pilcher, Lynne Alison, Balogun, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223974/
https://www.ncbi.nlm.nih.gov/pubmed/34063891
http://dx.doi.org/10.3390/life11060462