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Personalized Approach to Patient with MRI Brain Changes after SARS-CoV-2 Infection
From the beginning of SARS-CoV-2 virus pandemic, it was clear that respiratory symptoms are often accompanied with neurological symptoms. Neurological manifestations can occur even after mild forms of respiratory disease, and neurological symptoms are very often associated with worsening of the pati...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224015/ https://www.ncbi.nlm.nih.gov/pubmed/34063824 http://dx.doi.org/10.3390/jpm11060442 |
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author | Marcic, Ljiljana Marcic, Marino Kojundzic, Sanja Lovric Marcic, Barbara Capkun, Vesna Vukojevic, Katarina |
author_facet | Marcic, Ljiljana Marcic, Marino Kojundzic, Sanja Lovric Marcic, Barbara Capkun, Vesna Vukojevic, Katarina |
author_sort | Marcic, Ljiljana |
collection | PubMed |
description | From the beginning of SARS-CoV-2 virus pandemic, it was clear that respiratory symptoms are often accompanied with neurological symptoms. Neurological manifestations can occur even after mild forms of respiratory disease, and neurological symptoms are very often associated with worsening of the patient’s condition. The aim of this study was to show abnormal brain neuroimaging findings evaluated by MRI in patients after SARS-CoV-2 infection and neurological symptoms. Methods: Sixteen patients after mild forms of SARS-CoV-2 infection, twenty-three patients after moderate forms of SARS-CoV-2 infection as well as sixteen healthy participants in the control group underwent MRI 3T brain scan. All subjects in the SARS-CoV-2 group had small, punctuate, strategically located and newly formed hyperintense lesions on T2 and FLAIR sequences. New lesions were formed more often in the bilateral frontal subcortical and bilateral periventricular, correlated with the severity of the clinical picture. These changes indicate an example of silent cerebrovascular disease related to SARS-CoV-2 and once again emphasize the neurotropism of the virus. |
format | Online Article Text |
id | pubmed-8224015 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82240152021-06-25 Personalized Approach to Patient with MRI Brain Changes after SARS-CoV-2 Infection Marcic, Ljiljana Marcic, Marino Kojundzic, Sanja Lovric Marcic, Barbara Capkun, Vesna Vukojevic, Katarina J Pers Med Article From the beginning of SARS-CoV-2 virus pandemic, it was clear that respiratory symptoms are often accompanied with neurological symptoms. Neurological manifestations can occur even after mild forms of respiratory disease, and neurological symptoms are very often associated with worsening of the patient’s condition. The aim of this study was to show abnormal brain neuroimaging findings evaluated by MRI in patients after SARS-CoV-2 infection and neurological symptoms. Methods: Sixteen patients after mild forms of SARS-CoV-2 infection, twenty-three patients after moderate forms of SARS-CoV-2 infection as well as sixteen healthy participants in the control group underwent MRI 3T brain scan. All subjects in the SARS-CoV-2 group had small, punctuate, strategically located and newly formed hyperintense lesions on T2 and FLAIR sequences. New lesions were formed more often in the bilateral frontal subcortical and bilateral periventricular, correlated with the severity of the clinical picture. These changes indicate an example of silent cerebrovascular disease related to SARS-CoV-2 and once again emphasize the neurotropism of the virus. MDPI 2021-05-21 /pmc/articles/PMC8224015/ /pubmed/34063824 http://dx.doi.org/10.3390/jpm11060442 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Marcic, Ljiljana Marcic, Marino Kojundzic, Sanja Lovric Marcic, Barbara Capkun, Vesna Vukojevic, Katarina Personalized Approach to Patient with MRI Brain Changes after SARS-CoV-2 Infection |
title | Personalized Approach to Patient with MRI Brain Changes after SARS-CoV-2 Infection |
title_full | Personalized Approach to Patient with MRI Brain Changes after SARS-CoV-2 Infection |
title_fullStr | Personalized Approach to Patient with MRI Brain Changes after SARS-CoV-2 Infection |
title_full_unstemmed | Personalized Approach to Patient with MRI Brain Changes after SARS-CoV-2 Infection |
title_short | Personalized Approach to Patient with MRI Brain Changes after SARS-CoV-2 Infection |
title_sort | personalized approach to patient with mri brain changes after sars-cov-2 infection |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224015/ https://www.ncbi.nlm.nih.gov/pubmed/34063824 http://dx.doi.org/10.3390/jpm11060442 |
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