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Single Amino Acid Deletion at N-Terminus of the Target Antigen in DNA Vaccine Induces Altered CD8(+) T Cell Responses against Tumor Antigen
Since CD8(+) T cells have immunological memory and can eliminate tumor or infected cells, antigen-specific CD8(+) T cell inducing DNA vaccines are potential next-generation vaccines. However, the relationship between single amino acid deletion of target antigens in plasmid DNA vaccines and vaccine e...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224024/ https://www.ncbi.nlm.nih.gov/pubmed/34063920 http://dx.doi.org/10.3390/vaccines9060540 |