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Head-to-Head Comparison of Modular Vaccines Developed Using Different Capsid Virus-Like Particle Backbones and Antigen Conjugation Systems

Capsid virus-like particles (cVLPs) are used as molecular scaffolds to increase the immunogenicity of displayed antigens. Modular platforms have been developed whereby antigens are attached to the surface of pre-assembled cVLPs. However, it remains unknown to what extent the employed cVLP backbone a...

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Detalles Bibliográficos
Autores principales: Fredsgaard, Laurits, Goksøyr, Louise, Thrane, Susan, Aves, Kara-Lee, Theander, Thor G., Sander, Adam F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224050/
https://www.ncbi.nlm.nih.gov/pubmed/34063871
http://dx.doi.org/10.3390/vaccines9060539