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Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification

Calcification is a prominent feature of late-stage atherosclerosis, but the mechanisms driving this process are unclear. Using a biobank of carotid endarterectomies, we recently showed that Proteoglycan 4 (PRG4) is a key molecular signature of calcified plaques, expressed in smooth muscle cell (SMC)...

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Detalles Bibliográficos
Autores principales:	Seime, Till, Akbulut, Asim Cengiz, Liljeqvist, Moritz Lindquist, Siika, Antti, Jin, Hong, Winski, Greg, van Gorp, Rick H., Karlöf, Eva, Lengquist, Mariette, Buckler, Andrew J., Kronqvist, Malin, Waring, Olivia J., Lindeman, Jan H. N., Biessen, Erik A. L., Maegdefessel, Lars, Razuvaev, Anton, Schurgers, Leon J., Hedin, Ulf, Matic, Ljubica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224064/ https://www.ncbi.nlm.nih.gov/pubmed/34063989 http://dx.doi.org/10.3390/cells10061276

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