Cargando…

Interaction of Neuromelanin with Xenobiotics and Consequences for Neurodegeneration; Promising Experimental Models

Neuromelanin (NM) accumulates in catecholamine long-lived brain neurons that are lost in neurodegenerative diseases. NM is a complex substance made of melanic, peptide and lipid components. NM formation is a natural protective process since toxic endogenous metabolites are removed during its formati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Capucciati, Andrea, Zucca, Fabio A., Monzani, Enrico, Zecca, Luigi, Casella, Luigi, Hofer, Tim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224073/ https://www.ncbi.nlm.nih.gov/pubmed/34064062 http://dx.doi.org/10.3390/antiox10060824

Ejemplares similares

Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role
por: Zucca, Fabio A., et al.
Publicado: (2022)

Neuromelanins of Human Brain Have Soluble and Insoluble Components with Dolichols Attached to the Melanic Structure
por: Engelen, Mireille, et al.
Publicado: (2012)

The protective and toxic role of neuromelanins in brain aging and Parkinson’s disease
por: Zecca, Luigi, et al.
Publicado: (2015)

Tracemetals, neuromelanin and neurodegeneration: An interesting area for research
por: Sathyanarayana Rao, T. S., et al.
Publicado: (2007)

Neuromelanin detection by magnetic resonance imaging (MRI) and its promise as a biomarker for Parkinson’s disease
por: Sulzer, David, et al.
Publicado: (2018)

The role of tyrosine hydroxylase as a key player in neuromelanin synthesis and the association of neuromelanin with Parkinson’s disease
por: Nagatsu, Toshiharu, et al.
Publicado: (2023)

Norepinephrine and its metabolites are involved in the synthesis of neuromelanin derived from the locus coeruleus
por: Wakamatsu, Kazumasa, et al.
Publicado: (2015)

Neuromelanin organelles are specialized autolysosomes that accumulate undegraded proteins and lipids in aging human brain and are likely involved in Parkinson’s disease
por: Zucca, Fabio A., et al.
Publicado: (2018)

Reduction of the Nitro Group to Amine by Hydroiodic Acid to Synthesize o-Aminophenol Derivatives as Putative Degradative Markers of Neuromelanin
por: Wakamatsu, Kazumasa, et al.
Publicado: (2014)

Neuronal MHC-I display in T-cell mediated neurodegeneration
por: Cebrián, Carolina, et al.
Publicado: (2013)

Neuromelanin Imaging and Dopaminergic Loss in Parkinson's Disease
por: Isaias, Ioannis U., et al.
Publicado: (2016)

The Neuromelanin Paradox and Its Dual Role in Oxidative Stress and Neurodegeneration
por: Moreno-García, Alexandra, et al.
Publicado: (2021)

Neuromelanin-sensitive magnetic resonance imaging: a promising technique for depicting tissue characteristics containing neuromelanin
por: Nakamura, Ken, et al.
Publicado: (2014)

Interaction and Redox Chemistry between Iron, Dopamine, and Alpha-Synuclein C-Terminal Peptides
por: Schifano, Fabio, et al.
Publicado: (2023)

Interaction between Neuromelanin and Alpha-Synuclein in Parkinson’s Disease
por: Xu, Shengli, et al.
Publicado: (2015)

Fronto-striato-thalamic circuit connectivity and neuromelanin in schizophrenia: an fMRI and neuromelanin-MRI study
por: Choi, Sunah, et al.
Publicado: (2023)

Unraveling the contributions to the neuromelanin-MRI contrast
por: Priovoulos, Nikos, et al.
Publicado: (2020)

An investigation of neuromelanin distribution in substantia nigra and locus coeruleus in patients with Parkinson’s disease using neuromelanin-sensitive MRI
por: Liu, Qiang, et al.
Publicado: (2023)

Interaction between Hemin and Prion Peptides: Binding, Oxidative Reactivity and Aggregation
por: Dell’Acqua, Simone, et al.
Publicado: (2020)

Neuromelanin is an immune stimulator for dendritic cells in vitro
por: Oberländer, Uwe, et al.
Publicado: (2011)

Neuromelanin, aging, and neuronal vulnerability in Parkinson's disease
por: Vila, Miquel
Publicado: (2019)

Neuromelanin in Parkinson’s Disease: Tyrosine Hydroxylase and Tyrosinase
por: Nagatsu, Toshiharu, et al.
Publicado: (2022)

The Proteome of Neuromelanin Granules in Dementia with Lewy Bodies
por: Wulf, Maximilian, et al.
Publicado: (2022)

Application of Neuromelanin MR Imaging in Parkinson Disease
por: He, Naying, et al.
Publicado: (2022)

Xenobiotic metabolism and its physiological consequences in high-Antarctic Notothenioid fishes
por: Strobel, Anneli, et al.
Publicado: (2021)

Cannabinoids and Neurogenesis: The Promised Solution for Neurodegeneration?
por: Valeri, Andrea, et al.
Publicado: (2021)

Locus coeruleus neuromelanin accumulation and dissipation across the lifespan
por: Riley, Elizabeth, et al.
Publicado: (2023)

Asymmetric Sulfoxidation by a Tyrosinase Biomimetic Dicopper Complex with a Benzimidazolyl Derivative of L-Phenylalanine
por: Lo Presti, Eliana, et al.
Publicado: (2023)

Iron in Neurodegeneration – Cause or Consequence?
por: Ndayisaba, Alain, et al.
Publicado: (2019)

Molecular Interactions between NAFLD and Xenobiotic Metabolism
por: Naik, Adviti, et al.
Publicado: (2013)

The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism
por: Zhou, Changcheng, et al.
Publicado: (2009)

“Commandeuring” Xenobiotic Metabolism: Advances in Understanding Xenobiotic Metabolism
por: van Vugt-Lussenburg, Barbara M. A., et al.
Publicado: (2022)

The metal-nonoate Ni(SalPipNONO) inhibits in vitro tumor growth, invasiveness and angiogenesis
por: Ciccone, Valerio, et al.
Publicado: (2018)

Neuromelanin‐Sensitive Magnetic Resonance Imaging Using DANTE Pulse
por: Oshima, Sonoko, et al.
Publicado: (2020)

The spatiotemporal changes in dopamine, neuromelanin and iron characterizing Parkinson’s disease
por: Biondetti, Emma, et al.
Publicado: (2021)

Nigrosome and Neuromelanin Imaging as Tools to Differentiate Parkinson's Disease and Parkinsonism
por: Biswas, Deblina, et al.
Publicado: (2022)

Neuromelanin accumulation drives endogenous synucleinopathy in non-human primates
por: Chocarro, Julia, et al.
Publicado: (2023)

A Cu-bis(imidazole) Substrate Intermediate Is the Catalytically Competent Center for Catechol Oxidase Activity of Copper Amyloid-β
por: Bacchella, Chiara, et al.
Publicado: (2021)

Oxidase Reactivity of Cu(II) Bound to N-Truncated Aβ Peptides Promoted by Dopamine
por: Bacchella, Chiara, et al.
Publicado: (2021)

The promise and perils of HDAC inhibitors in neurodegeneration
por: Didonna, Alessandro, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_55og7hjn0tgsvbnv6nsd6ifer8