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Towards a Functional Neuromarker of Impulsivity: Feedback-Related Brain Potential during Risky Decision-Making Associated with Self-Reported Impulsivity in a Non-Clinical Sample

Risk-taking is part of the multidimensional nature of impulsivity, consisting of an active engagement in behaviors or choices with potentially undesirable results, with probability as the cost for an expected reward. In order to understand the neurophysiological activity during risky behavior and it...

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Autores principales: Teti Mayer, Juliana, Compagne, Charline, Nicolier, Magali, Grandperrin, Yohan, Chabin, Thibault, Giustiniani, Julie, Haffen, Emmanuel, Bennabi, Djamila, Gabriel, Damien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224100/
https://www.ncbi.nlm.nih.gov/pubmed/34063798
http://dx.doi.org/10.3390/brainsci11060671
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author Teti Mayer, Juliana
Compagne, Charline
Nicolier, Magali
Grandperrin, Yohan
Chabin, Thibault
Giustiniani, Julie
Haffen, Emmanuel
Bennabi, Djamila
Gabriel, Damien
author_facet Teti Mayer, Juliana
Compagne, Charline
Nicolier, Magali
Grandperrin, Yohan
Chabin, Thibault
Giustiniani, Julie
Haffen, Emmanuel
Bennabi, Djamila
Gabriel, Damien
author_sort Teti Mayer, Juliana
collection PubMed
description Risk-taking is part of the multidimensional nature of impulsivity, consisting of an active engagement in behaviors or choices with potentially undesirable results, with probability as the cost for an expected reward. In order to understand the neurophysiological activity during risky behavior and its relationship with other dimensions of impulsivity, we have acquired event-related-potential (ERP) data and self-reported impulsivity scores from 17 non-clinical volunteers. They underwent high-resolution electroencephalography (HR-EEG) combined with an adapted version of the Balloon Analogue Risk Task (BART), and completed the Barratt Impulsiveness Scale (BIS-10) and the Urgency, Premeditation, Perseverance, Sensation Seeking, Impulsive Behavior Scale (UPPS). The ERP components were sensitive to valence (FRN, P300) and risk/reward magnitude (SPN, RewP). Our main finding evidenced a positive correlation between the amplitude of the P300 component following positive feedback and both the global UPPS score and the (lack of) perseverance UPPS subscale, significant for several adjacent electrodes. This finding might suggest an adaptive form of impulsive behavior, which could be associated to the reduction on the difference of the P300 amplitude following negative and positive feedback. However, further investigation with both larger clinical and non-clinical samples is required.
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spelling pubmed-82241002021-06-25 Towards a Functional Neuromarker of Impulsivity: Feedback-Related Brain Potential during Risky Decision-Making Associated with Self-Reported Impulsivity in a Non-Clinical Sample Teti Mayer, Juliana Compagne, Charline Nicolier, Magali Grandperrin, Yohan Chabin, Thibault Giustiniani, Julie Haffen, Emmanuel Bennabi, Djamila Gabriel, Damien Brain Sci Article Risk-taking is part of the multidimensional nature of impulsivity, consisting of an active engagement in behaviors or choices with potentially undesirable results, with probability as the cost for an expected reward. In order to understand the neurophysiological activity during risky behavior and its relationship with other dimensions of impulsivity, we have acquired event-related-potential (ERP) data and self-reported impulsivity scores from 17 non-clinical volunteers. They underwent high-resolution electroencephalography (HR-EEG) combined with an adapted version of the Balloon Analogue Risk Task (BART), and completed the Barratt Impulsiveness Scale (BIS-10) and the Urgency, Premeditation, Perseverance, Sensation Seeking, Impulsive Behavior Scale (UPPS). The ERP components were sensitive to valence (FRN, P300) and risk/reward magnitude (SPN, RewP). Our main finding evidenced a positive correlation between the amplitude of the P300 component following positive feedback and both the global UPPS score and the (lack of) perseverance UPPS subscale, significant for several adjacent electrodes. This finding might suggest an adaptive form of impulsive behavior, which could be associated to the reduction on the difference of the P300 amplitude following negative and positive feedback. However, further investigation with both larger clinical and non-clinical samples is required. MDPI 2021-05-21 /pmc/articles/PMC8224100/ /pubmed/34063798 http://dx.doi.org/10.3390/brainsci11060671 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Teti Mayer, Juliana
Compagne, Charline
Nicolier, Magali
Grandperrin, Yohan
Chabin, Thibault
Giustiniani, Julie
Haffen, Emmanuel
Bennabi, Djamila
Gabriel, Damien
Towards a Functional Neuromarker of Impulsivity: Feedback-Related Brain Potential during Risky Decision-Making Associated with Self-Reported Impulsivity in a Non-Clinical Sample
title Towards a Functional Neuromarker of Impulsivity: Feedback-Related Brain Potential during Risky Decision-Making Associated with Self-Reported Impulsivity in a Non-Clinical Sample
title_full Towards a Functional Neuromarker of Impulsivity: Feedback-Related Brain Potential during Risky Decision-Making Associated with Self-Reported Impulsivity in a Non-Clinical Sample
title_fullStr Towards a Functional Neuromarker of Impulsivity: Feedback-Related Brain Potential during Risky Decision-Making Associated with Self-Reported Impulsivity in a Non-Clinical Sample
title_full_unstemmed Towards a Functional Neuromarker of Impulsivity: Feedback-Related Brain Potential during Risky Decision-Making Associated with Self-Reported Impulsivity in a Non-Clinical Sample
title_short Towards a Functional Neuromarker of Impulsivity: Feedback-Related Brain Potential during Risky Decision-Making Associated with Self-Reported Impulsivity in a Non-Clinical Sample
title_sort towards a functional neuromarker of impulsivity: feedback-related brain potential during risky decision-making associated with self-reported impulsivity in a non-clinical sample
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224100/
https://www.ncbi.nlm.nih.gov/pubmed/34063798
http://dx.doi.org/10.3390/brainsci11060671
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