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Repeated Aconitine Treatment Induced the Remodeling of Mitochondrial Function via AMPK–OPA1–ATP5A1 Pathway

Aconitine is attracting increasing attention for its unique positive inotropic effect on the cardiovascular system, but underlying molecular mechanisms are still not fully understood. The cardiotonic effect always requires abundant energy supplement, which is mainly related to mitochondrial function...

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Detalles Bibliográficos
Autores principales: Qiu, Li-Zhen, Zhou, Wei, Yue, Lan-Xin, Wang, Yi-Hao, Hao, Fei-Ran, Li, Peng-Yan, Gao, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224173/
https://www.ncbi.nlm.nih.gov/pubmed/34177570
http://dx.doi.org/10.3389/fphar.2021.646121