Cargando…
Repeated Aconitine Treatment Induced the Remodeling of Mitochondrial Function via AMPK–OPA1–ATP5A1 Pathway
Aconitine is attracting increasing attention for its unique positive inotropic effect on the cardiovascular system, but underlying molecular mechanisms are still not fully understood. The cardiotonic effect always requires abundant energy supplement, which is mainly related to mitochondrial function...
Autores principales: | Qiu, Li-Zhen, Zhou, Wei, Yue, Lan-Xin, Wang, Yi-Hao, Hao, Fei-Ran, Li, Peng-Yan, Gao, Yue |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224173/ https://www.ncbi.nlm.nih.gov/pubmed/34177570 http://dx.doi.org/10.3389/fphar.2021.646121 |
Ejemplares similares
-
CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism
por: Xie, Tianqi, et al.
Publicado: (2020) -
Compatibility of Fuzi and Ginseng Significantly Increase the Exposure of Aconitines
por: Chen, Ze-Yan, et al.
Publicado: (2022) -
Sweroside Alleviated Aconitine-Induced Cardiac Toxicity in H9c2 Cardiomyoblast Cell Line
por: Ma, Li-Qun, et al.
Publicado: (2018) -
In situ architecture of Opa1-dependent mitochondrial cristae remodeling
por: Fry, Michelle Y., et al.
Publicado: (2023) -
Involvement of Nrf2-HO-1/JNK-Erk Signaling Pathways in Aconitine-Induced Developmental Toxicity, Oxidative Stress, and ROS-Mitochondrial Apoptosis in Zebrafish Embryos
por: Xia, Qing, et al.
Publicado: (2021)