Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes

The molecular composition and binding epitopes of the immunoglobulin G (IgG) antibodies that circulate in blood plasma following SARS-CoV-2 infection are unknown. Proteomic deconvolution of the IgG repertoire to the spike glycoprotein in convalescent subjects revealed that the response is directed p...

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Detalles Bibliográficos
Autores principales: Voss, William N., Hou, Yixuan J., Johnson, Nicole V., Delidakis, George, Kim, Jin Eyun, Javanmardi, Kamyab, Horton, Andrew P., Bartzoka, Foteini, Paresi, Chelsea J., Tanno, Yuri, Chou, Chia-Wei, Abbasi, Shawn A., Pickens, Whitney, George, Katia, Boutz, Daniel R., Towers, Dalton M., McDaniel, Jonathan R., Billick, Daniel, Goike, Jule, Rowe, Lori, Batra, Dhwani, Pohl, Jan, Lee, Justin, Gangappa, Shivaprakash, Sambhara, Suryaprakash, Gadush, Michelle, Wang, Nianshuang, Person, Maria D., Iverson, Brent L., Gollihar, Jimmy D., Dye, John, Herbert, Andrew, Finkelstein, Ilya J., Baric, Ralph S., McLellan, Jason S., Georgiou, George, Lavinder, Jason J., Ippolito, Gregory C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224265/
https://www.ncbi.nlm.nih.gov/pubmed/33947773
http://dx.doi.org/10.1126/science.abg5268

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