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Oncolytic Vaccinia Virus Expressing White-Spotted Charr Lectin Regulates Antiviral Response in Tumor Cells and Inhibits Tumor Growth In Vitro and In Vivo

Oncolytic vaccina virus (oncoVV) used for cancer therapy has progressed in recent years. Here, a gene encoding white-spotted charr lectin (WCL) was inserted into an oncoVV vector to form an oncoVV-WCL recombinant virus. OncoVV-WCL induced higher levels of apoptosis and cytotoxicity, and replicated f...

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Detalles Bibliográficos
Autores principales:	Wang, Xue, Zhou, Ningning, Liu, Tingting, Jia, Xiaoyuan, Ye, Ting, Chen, Kan, Li, Gongchu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224321/ https://www.ncbi.nlm.nih.gov/pubmed/34064193 http://dx.doi.org/10.3390/md19060292

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