Shear Wave Elastography in the Detection of Sinusoidal Obstruction Syndrome in Adult Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation

Hepatic sinusoidal obstruction syndrome (SOS), also known as veno-occlusive disease (VOD) can be a life-threatening complication after hematopoietic stem cell transplantation (HSCT). Diagnosis is often difficult and traditionally based on clinical parameters. Shear wave elastography (SWE) is a moder...

Descripción completa

Detalles Bibliográficos
Autores principales: Schulz, Marten, Vuong, Lam Giang, Müller, Hans Peter, Maibier, Martin, Tacke, Frank, Blau, Igor Wolfgang, Wree, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224360/
https://www.ncbi.nlm.nih.gov/pubmed/34064217
http://dx.doi.org/10.3390/diagnostics11060928
_version_ 1783711872832241664
author Schulz, Marten
Vuong, Lam Giang
Müller, Hans Peter
Maibier, Martin
Tacke, Frank
Blau, Igor Wolfgang
Wree, Alexander
author_facet Schulz, Marten
Vuong, Lam Giang
Müller, Hans Peter
Maibier, Martin
Tacke, Frank
Blau, Igor Wolfgang
Wree, Alexander
author_sort Schulz, Marten
collection PubMed
description Hepatic sinusoidal obstruction syndrome (SOS), also known as veno-occlusive disease (VOD) can be a life-threatening complication after hematopoietic stem cell transplantation (HSCT). Diagnosis is often difficult and traditionally based on clinical parameters. Shear wave elastography (SWE) is a modern non-invasive liver stiffness measurement technique using ultrasound. In this monocentric study, we evaluated the role of SWE in diagnosing SOS/VOD in 63 adult patients undergoing HSCT from February 2020 to August 2020 in real world settings. Three patients developed SOS/VOD. This was accompanied by an increase in shear wave velocity in all three patients, indicating that this method may contribute to establishing the diagnosis SOS/VOD after HSCT.
format Online
Article
Text
id pubmed-8224360
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-82243602021-06-25 Shear Wave Elastography in the Detection of Sinusoidal Obstruction Syndrome in Adult Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation Schulz, Marten Vuong, Lam Giang Müller, Hans Peter Maibier, Martin Tacke, Frank Blau, Igor Wolfgang Wree, Alexander Diagnostics (Basel) Article Hepatic sinusoidal obstruction syndrome (SOS), also known as veno-occlusive disease (VOD) can be a life-threatening complication after hematopoietic stem cell transplantation (HSCT). Diagnosis is often difficult and traditionally based on clinical parameters. Shear wave elastography (SWE) is a modern non-invasive liver stiffness measurement technique using ultrasound. In this monocentric study, we evaluated the role of SWE in diagnosing SOS/VOD in 63 adult patients undergoing HSCT from February 2020 to August 2020 in real world settings. Three patients developed SOS/VOD. This was accompanied by an increase in shear wave velocity in all three patients, indicating that this method may contribute to establishing the diagnosis SOS/VOD after HSCT. MDPI 2021-05-21 /pmc/articles/PMC8224360/ /pubmed/34064217 http://dx.doi.org/10.3390/diagnostics11060928 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Schulz, Marten
Vuong, Lam Giang
Müller, Hans Peter
Maibier, Martin
Tacke, Frank
Blau, Igor Wolfgang
Wree, Alexander
Shear Wave Elastography in the Detection of Sinusoidal Obstruction Syndrome in Adult Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation
title Shear Wave Elastography in the Detection of Sinusoidal Obstruction Syndrome in Adult Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation
title_full Shear Wave Elastography in the Detection of Sinusoidal Obstruction Syndrome in Adult Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation
title_fullStr Shear Wave Elastography in the Detection of Sinusoidal Obstruction Syndrome in Adult Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation
title_full_unstemmed Shear Wave Elastography in the Detection of Sinusoidal Obstruction Syndrome in Adult Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation
title_short Shear Wave Elastography in the Detection of Sinusoidal Obstruction Syndrome in Adult Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation
title_sort shear wave elastography in the detection of sinusoidal obstruction syndrome in adult patients undergoing allogenic hematopoietic stem cell transplantation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224360/
https://www.ncbi.nlm.nih.gov/pubmed/34064217
http://dx.doi.org/10.3390/diagnostics11060928
work_keys_str_mv AT schulzmarten shearwaveelastographyinthedetectionofsinusoidalobstructionsyndromeinadultpatientsundergoingallogenichematopoieticstemcelltransplantation
AT vuonglamgiang shearwaveelastographyinthedetectionofsinusoidalobstructionsyndromeinadultpatientsundergoingallogenichematopoieticstemcelltransplantation
AT mullerhanspeter shearwaveelastographyinthedetectionofsinusoidalobstructionsyndromeinadultpatientsundergoingallogenichematopoieticstemcelltransplantation
AT maibiermartin shearwaveelastographyinthedetectionofsinusoidalobstructionsyndromeinadultpatientsundergoingallogenichematopoieticstemcelltransplantation
AT tackefrank shearwaveelastographyinthedetectionofsinusoidalobstructionsyndromeinadultpatientsundergoingallogenichematopoieticstemcelltransplantation
AT blauigorwolfgang shearwaveelastographyinthedetectionofsinusoidalobstructionsyndromeinadultpatientsundergoingallogenichematopoieticstemcelltransplantation
AT wreealexander shearwaveelastographyinthedetectionofsinusoidalobstructionsyndromeinadultpatientsundergoingallogenichematopoieticstemcelltransplantation

Ejemplares similares