A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms

Pseudomonas aeruginosa (PA) infections can be notoriously difficult to treat and are often accompanied by the development of antimicrobial resistance (AMR). Quorum sensing inhibitors (QSI) acting on PqsR (MvfR) – a crucial transcriptional regulator serving major functions in PA virulence – can enhan...

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Detalles Bibliográficos
Autores principales: Schütz, Christian, Ho, Duy‐Khiet, Hamed, Mostafa Mohamed, Abdelsamie, Ahmed Saad, Röhrig, Teresa, Herr, Christian, Kany, Andreas Martin, Rox, Katharina, Schmelz, Stefan, Siebenbürger, Lorenz, Wirth, Marius, Börger, Carsten, Yahiaoui, Samir, Bals, Robert, Scrima, Andrea, Blankenfeldt, Wulf, Horstmann, Justus Constantin, Christmann, Rebekka, Murgia, Xabier, Koch, Marcus, Berwanger, Aylin, Loretz, Brigitta, Hirsch, Anna Katharina Herta, Hartmann, Rolf Wolfgang, Lehr, Claus‐Michael, Empting, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224453/
https://www.ncbi.nlm.nih.gov/pubmed/34165899
http://dx.doi.org/10.1002/advs.202004369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224453/
https://www.ncbi.nlm.nih.gov/pubmed/34165899
http://dx.doi.org/10.1002/advs.202004369

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