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Persistence of Coxsackievirus B4 in Pancreatic β Cells Disturbs Insulin Maturation, Pattern of Cellular Proteins, and DNA Methylation
Coxsackievirus-B4 (CV-B4) can persist in pancreatic cell lines and impair the phenoytpe and/or gene expressions in these cells; however, the models used to study this phenomenon did not produce insulin. Therefore, we investigated CV-B4 persistence and its consequences in insulin-producing pancreatic...
Autores principales: | Nekoua, Magloire Pandoua, Bertin, Antoine, Sane, Famara, Gimeno, Jean-Pascal, Fournier, Isabelle, Salzet, Michel, Engelmann, Ilka, Alidjinou, Enagnon Kazali, Hober, Didier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224704/ https://www.ncbi.nlm.nih.gov/pubmed/34067388 http://dx.doi.org/10.3390/microorganisms9061125 |
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