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An image-based flow cytometric approach to the assessment of the nucleus-to-cytoplasm ratio

The nucleus-to-cytoplasm ratio (N:C) can be used as one metric in histology for grading certain types of tumor malignancy. Current N:C assessment techniques are time-consuming and low throughput. Thus, in high-throughput clinical contexts, there is a need for a technique that can assess cell maligna...

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Detalles Bibliográficos
Autores principales: Sebastian, Joseph A., Moore, Michael J., Berndl, Elizabeth S. L., Kolios, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224973/
https://www.ncbi.nlm.nih.gov/pubmed/34166419
http://dx.doi.org/10.1371/journal.pone.0253439