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Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment

Raloxifene hydrochloride (RLX), an antiosteoporotic agent, has been utilized for guarding against breast cancer and recently, for the disease management owing to its estrogen antagonist activity. Nevertheless, RLX exhibits poor bioavailability that could be attributed to reduced water solubility and...

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Detalles Bibliográficos
Autores principales: Aldawsari, Hibah M., Ahmed, Osama A. A., Alhakamy, Nabil A., Neamatallah, Thikryat, Fahmy, Usama A., Badr-Eldin, Shaimaa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225169/
https://www.ncbi.nlm.nih.gov/pubmed/34073780
http://dx.doi.org/10.3390/pharmaceutics13060783