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Involvement of mTOR Pathways in Recovery from Spinal Cord Injury by Modulation of Autophagy and Immune Response

Traumatic spinal cord injury (SCI) is untreatable and remains the leading cause of disability. Neuroprotection and recovery after SCI can be partially achieved by rapamycin (RAPA) treatment, an inhibitor of mTORC1, complex 1 of the mammalian target of rapamycin (mTOR) pathway. However, mechanisms re...

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Detalles Bibliográficos
Autores principales: Vargova, Ingrid, Machova Urdzikova, Lucia, Karova, Kristyna, Smejkalova, Barbora, Sursal, Tolga, Cimermanova, Veronika, Turnovcova, Karolina, Gandhi, Chirag D., Jhanwar-Uniyal, Meena, Jendelova, Pavla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225190/
https://www.ncbi.nlm.nih.gov/pubmed/34073791
http://dx.doi.org/10.3390/biomedicines9060593