Mitochondrial Succinate Metabolism and Reactive Oxygen Species Are Important but Not Essential for Eliciting Carotid Body and Ventilatory Responses to Hypoxia in the Rat

Reflex increases in breathing in response to acute hypoxia are dependent on activation of the carotid body (CB)—A specialised peripheral chemoreceptor. Central to CB O(2)-sensing is their unique mitochondria but the link between mitochondrial inhibition and cellular stimulation is unresolved. The ob...

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Detalles Bibliográficos
Autores principales: Swiderska, Agnieszka, Coney, Andrew M., Alzahrani, Abdulaziz A., Aldossary, Hayyaf S., Batis, Nikolaos, Ray, Clare J., Kumar, Prem, Holmes, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225218/
https://www.ncbi.nlm.nih.gov/pubmed/34070267
http://dx.doi.org/10.3390/antiox10060840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225218/
https://www.ncbi.nlm.nih.gov/pubmed/34070267
http://dx.doi.org/10.3390/antiox10060840

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