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Mitochondrial Succinate Metabolism and Reactive Oxygen Species Are Important but Not Essential for Eliciting Carotid Body and Ventilatory Responses to Hypoxia in the Rat
Reflex increases in breathing in response to acute hypoxia are dependent on activation of the carotid body (CB)—A specialised peripheral chemoreceptor. Central to CB O(2)-sensing is their unique mitochondria but the link between mitochondrial inhibition and cellular stimulation is unresolved. The ob...
Autores principales: | Swiderska, Agnieszka, Coney, Andrew M., Alzahrani, Abdulaziz A., Aldossary, Hayyaf S., Batis, Nikolaos, Ray, Clare J., Kumar, Prem, Holmes, Andrew P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225218/ https://www.ncbi.nlm.nih.gov/pubmed/34070267 http://dx.doi.org/10.3390/antiox10060840 |
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