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Autocrine Effects of Brain Endothelial Cell-Produced Human Apolipoprotein E on Metabolism and Inflammation in vitro

Reports of APOE4-associated neurovascular dysfunction during aging and in neurodegenerative disorders has led to ongoing research to identify underlying mechanisms. In this study, we focused on whether the APOE genotype of brain endothelial cells modulates their own phenotype. We utilized a modified...

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Detalles Bibliográficos
Autores principales:	Marottoli, Felecia M., Trevino, Troy N., Geng, Xue, Arbieva, Zarema, Kanabar, Pinal, Maienschein-Cline, Mark, Lee, James C., Lutz, Sarah E., Tai, Leon M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225247/ https://www.ncbi.nlm.nih.gov/pubmed/34178992 http://dx.doi.org/10.3389/fcell.2021.668296

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