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Double-strand breaks induce short-scale DNA replication and damage amplification in the fully grown mouse oocytes

Break-induced replication (BIR) is essential for the repair of DNA double-strand breaks (DSBs) with single ends. DSBs-induced microhomology-mediated BIR (mmBIR) and template-switching can increase the risk of complex genome rearrangement. In addition, DSBs can also induce the multi-invasion-mediated...

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Detalles Bibliográficos
Autores principales:	Ma, Jun-Yu, Feng, Xie, Xie, Feng-Yun, Li, Sen, Chen, Lei-Ning, Luo, Shi-Ming, Yin, Shen, Ou, Xiang-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225347/ https://www.ncbi.nlm.nih.gov/pubmed/33792683 http://dx.doi.org/10.1093/genetics/iyab054

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