Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis

The concept that extracellular vesicles (EVs) from the diet can be absorbed by the intestinal tract of the consuming organism, be bioavailable in various organs, and in-turn exert phenotypic changes is highly debatable. Here, we isolate EVs from both raw and commercial bovine milk and characterize t...

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Detalles Bibliográficos
Autores principales: Samuel, Monisha, Fonseka, Pamali, Sanwlani, Rahul, Gangoda, Lahiru, Chee, Sing Ho, Keerthikumar, Shivakumar, Spurling, Alex, Chitti, Sai V., Zanker, Damien, Ang, Ching-Seng, Atukorala, Ishara, Kang, Taeyoung, Shahi, Sanjay, Marzan, Akbar L., Nedeva, Christina, Vennin, Claire, Lucas, Morghan C., Cheng, Lesley, Herrmann, David, Pathan, Mohashin, Chisanga, David, Warren, Sean C., Zhao, Kening, Abraham, Nidhi, Anand, Sushma, Boukouris, Stephanie, Adda, Christopher G., Jiang, Lanzhou, Shekhar, Tanmay M., Baschuk, Nikola, Hawkins, Christine J., Johnston, Amelia J., Orian, Jacqueline Monique, Hoogenraad, Nicholas J., Poon, Ivan K., Hill, Andrew F., Jois, Markandeya, Timpson, Paul, Parker, Belinda S., Mathivanan, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225634/
https://www.ncbi.nlm.nih.gov/pubmed/34168137
http://dx.doi.org/10.1038/s41467-021-24273-8

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