Cargando…

Antiretroviral therapy for HIV controllers: Reasons for initiation and outcomes in the French ANRS-CO21 CODEX cohort

BACKGROUND: Less than 1% of Human Immunodeficiency Virus (HIV)-infected individuals are able to achieve spontaneous viral control without requiring antiretroviral therapy (ART). Whether these HIV controllers (HIC) are at risk of HIV-associated comorbidities and could benefit from ART is debated, but...

Descripción completa

Detalles Bibliográficos
Autores principales:	Plaçais, Léo, Boufassa, Faroudy, Lécuroux, Camille, Gardiennet, Elise, Avettand-Fenoel, Véronique, Saez-Cirion, Asier, Lambotte, Olivier, Noël, Nicolas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225698/ https://www.ncbi.nlm.nih.gov/pubmed/34195579 http://dx.doi.org/10.1016/j.eclinm.2021.100963

Ejemplares similares

Immunologic and Virologic Progression in HIV Controllers: The Role of Viral “Blips” and Immune Activation in the ANRS CO21 CODEX Study
por: Noel, Nicolas, et al.
Publicado: (2015)

CD4 Dynamics over a 15 Year-Period among HIV Controllers Enrolled in the ANRS French Observatory
por: Boufassa, Faroudy, et al.
Publicado: (2011)

A Subset of Extreme Human Immunodeficiency Virus (HIV) Controllers Is Characterized by a Small HIV Blood Reservoir and a Weak T-Cell Activation Level
por: Canouï, Etienne, et al.
Publicado: (2017)

Dynamics in HIV‐DNA levels over time in HIV controllers
por: Avettand‐Fenoel, Véronique, et al.
Publicado: (2019)

Post-Treatment HIV-1 Controllers with a Long-Term Virological Remission after the Interruption of Early Initiated Antiretroviral Therapy ANRS VISCONTI Study
por: Sáez-Cirión, Asier, et al.
Publicado: (2013)

In-Depth Characterization of Full-Length Archived Viral Genomes after Nine Years of Posttreatment HIV Control
por: Trémeaux, Pauline, et al.
Publicado: (2023)

Potential Role for HIV-Specific CD38(−)/HLA-DR(+) CD8(+) T Cells in Viral Suppression and Cytotoxicity in HIV Controllers
por: Hua, Stéphane, et al.
Publicado: (2014)

Non-AIDS-Defining Events in Human Immunodeficiency Virus Controllers Versus Antiretroviral Therapy–Controlled Patients: A Cohort Collaboration From the French National Agency for Research on AIDS CO21 (CODEX) and CO06 (PRIMO) Cohorts
por: Manto, Carmelite, et al.
Publicado: (2023)

Prolonged Antiretroviral Treatment Induces Adipose Tissue Remodelling Associated with Mild Inflammation in SIV-Infected Macaques
por: Mausoléo, Aude, et al.
Publicado: (2022)

Distinct Genetic Loci Control Plasma HIV-RNA and Cellular HIV-DNA Levels in HIV-1 Infection: The ANRS Genome Wide Association 01 Study
por: Dalmasso, Cyril, et al.
Publicado: (2008)

Blunted Response to Combination Antiretroviral Therapy in HIV Elite Controllers: An International HIV Controller Collaboration
por: Boufassa, Faroudy, et al.
Publicado: (2014)

High Antibody-Dependent Cellular Cytotoxicity Responses Are Correlated with Strong CD8 T Cell Viral Suppressive Activity but Not with B57 Status in HIV-1 Elite Controllers
por: Lambotte, Olivier, et al.
Publicado: (2013)

The potential role of HIV-specific CD38-/HLA-DR+ CD8+ T cells in viral suppressive activity and cytotoxicity in HIV controllers
por: Hua, Stéphane, et al.
Publicado: (2014)

Enhanced immunovirological response in women compared to men after antiretroviral therapy initiation during acute and early HIV‐1 infection: results from a longitudinal study in the French ANRS Primo cohort
por: Novelli, Sophie, et al.
Publicado: (2020)

Analysis of NKp30/NCR3 isoforms in untreated HIV-1-infected patients from the ANRS SEROCO cohort
por: Prada, Nicole, et al.
Publicado: (2013)

NKG2C(+) memory-like NK cells contribute to the control of HIV viremia during primary infection: Optiprim-ANRS 147
por: Gondois-Rey, Françoise, et al.
Publicado: (2017)

A Pilot Study of the Humoral Response Against the AntiSense Protein (ASP) in HIV-1-Infected Patients
por: Savoret, Juliette, et al.
Publicado: (2020)

Mass Cytometry Analysis Reveals the Landscape and Dynamics of CD32a(+) CD4(+) T Cells From Early HIV Infection to Effective cART
por: Coindre, Sixtine, et al.
Publicado: (2018)

Pro-viral DNA and antiretroviral treatment simplification
por: Zucman, D, et al.
Publicado: (2010)

HIV-Specific B Cell Frequency Correlates with Neutralization Breadth in Patients Naturally Controlling HIV-Infection
por: Rouers, Angeline, et al.
Publicado: (2017)

Increasing contribution of integrated forms to total HIV DNA in blood during HIV disease progression from primary infection
por: Trémeaux, Pauline, et al.
Publicado: (2019)

Reprogramming dysfunctional CD8(+) T cells to promote properties associated with natural HIV control
por: Perdomo-Celis, Federico, et al.
Publicado: (2022)

Reprogramming dysfunctional CD8(+) T cells to promote properties associated with natural HIV control
por: Perdomo-Celis, Federico, et al.
Publicado: (2023)

Impact of Early Versus Late Antiretroviral Treatment Initiation on Naive T Lymphocytes in HIV-1-Infected Children and Adolescents – The-ANRS-EP59-CLEAC Study
por: Frange, Pierre, et al.
Publicado: (2021)

Dendritic Cells from HIV Controllers Have Low Susceptibility to HIV-1 Infection In Vitro but High Capacity to Capture HIV-1 Particles
por: Hamimi, Chiraz, et al.
Publicado: (2016)

Associations between 25-Hydroxyvitamin D and Immunologic, Metabolic, Inflammatory Markers in Treatment-Naive HIV-Infected Persons: The ANRS CO9 «COPANA» Cohort Study
por: Legeai, Camille, et al.
Publicado: (2013)

Total HIV DNA: a global marker of HIV persistence
por: Rouzioux, Christine, et al.
Publicado: (2018)

Maintenance darunavir/ritonavir monotherapy to prevent perinatal HIV transmission, ANRS-MIE 168 MONOGEST study
por: Mandelbrot, Laurent, et al.
Publicado: (2023)

CD8 T-Cells from Most HIV-Infected Patients Lack Ex Vivo HIV-Suppressive Capacity during Acute and Early Infection
por: Lécuroux, Camille, et al.
Publicado: (2013)

Codex alimentarius = Commision du codex alimentarius = Comisión del codex alimentarius
Publicado: (1994)

Gag-Specific CD4 and CD8 T-Cell Proliferation in Adolescents and Young Adults with Perinatally Acquired HIV-1 Infection Is Associated with Ethnicity — The ANRS-EP38-IMMIP Study
por: Le Chenadec, Jérôme, et al.
Publicado: (2015)

Persistence of monocyte activation under treatment in people followed since acute HIV-1 infection relative to participants at high or low risk of HIV infection
por: Novelli, Sophie, et al.
Publicado: (2020)

P16-37. HIV controllers with weak CD8+ T cell responses maintain a tight control of infection despite carrying infectious viruses
por: Saez-Cirion, A, et al.
Publicado: (2009)

MELD Score Kinetics in Decompensated HIV+/HCV+ Patients: A Useful Prognostic Tool (ANRS HC EP 25 PRETHEVIC Cohort Study)
por: Gelu-Simeon, Moana, et al.
Publicado: (2015)

Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset
por: Ploquin, Mickaël J., et al.
Publicado: (2016)

The role of cytotoxic T cells
por: Sáez-Cirión, Asier
Publicado: (2010)

P16-45. High avidity CD4+ T cell response directed to an immunodominant Gag epitope in HIV controllers: an ANRS EP36 study
por: Vingert, B, et al.
Publicado: (2009)

Codex alimentarius
Publicado: (1995)

The Codex Mendoza
Publicado: (1992)

Codex alimentarius
Publicado: (1992)

Cannot write session to /tmp/vufind_sessions/sess_3t2b8f49e555fth2q2vo8ao7us