Structural insight into the unique conformation of cystathionine β-synthase from Toxoplasma gondii

Cysteine plays a major role in the redox homeostasis and antioxidative defense mechanisms of many parasites of the phylum Apicomplexa. Of relevance to human health is Toxoplasma gondii, the causative agent of toxoplasmosis. A major route of cysteine biosynthesis in this parasite is the reverse trans...

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Detalles Bibliográficos
Autores principales: Fernández-Rodríguez, Carmen, Oyenarte, Iker, Conter, Carolina, González-Recio, Irene, Núñez-Franco, Reyes, Gil-Pitarch, Claudia, Quintana, Iban, Jiménez-Osés, Gonzalo, Dominici, Paola, Martinez-Chantar, Maria Luz, Astegno, Alessandra, Martínez-Cruz, Luis Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225704/
https://www.ncbi.nlm.nih.gov/pubmed/34194677
http://dx.doi.org/10.1016/j.csbj.2021.05.052

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