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Preservation of renal endothelial integrity and reduction of renal edema by aprotinin does not preserve renal perfusion and function following experimental cardiopulmonary bypass

BACKGROUND: Acute kidney injury is a severe complication following cardiopulmonary bypass (CPB) and is associated with capillary leakage and microcirculatory perfusion disturbances. CPB-induced thrombin release results in capillary hyperpermeability via activation of protease-activated receptor 1 (P...

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Detalles Bibliográficos
Autores principales:	Dekker, Nicole A. M., van Leeuwen, Anoek L. I., van Meurs, Matijs, Moser, Jill, Pankras, Jeannette E., van der Wel, Nicole N., Niessen, Hans W., Vervloet, Marc G., Vonk, Alexander B. A., Hordijk, Peter L., Boer, Christa, van den Brom, Charissa E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225734/ https://www.ncbi.nlm.nih.gov/pubmed/34169407 http://dx.doi.org/10.1186/s40635-021-00393-9

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