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Healthcare-related impact of gout in hospitalized patients in Spain

To analyze the epidemiology, clinical features and costs of hospitalized patients with gout during the last decade in Spain. Retrospective observational study based on data from the Minimum Basic Data Set (MBDS) from the Spanish National Health Service database. Patients ≥ 18 years with any gout dia...

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Autores principales: Benavent, Diego, Peiteado, Diana, Martinez-Huedo, María Ángeles, Hernandez-Hurtado, María, Balsa, Alejandro, de Miguel, Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225766/
https://www.ncbi.nlm.nih.gov/pubmed/34168227
http://dx.doi.org/10.1038/s41598-021-92673-3
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author Benavent, Diego
Peiteado, Diana
Martinez-Huedo, María Ángeles
Hernandez-Hurtado, María
Balsa, Alejandro
de Miguel, Eugenio
author_facet Benavent, Diego
Peiteado, Diana
Martinez-Huedo, María Ángeles
Hernandez-Hurtado, María
Balsa, Alejandro
de Miguel, Eugenio
author_sort Benavent, Diego
collection PubMed
description To analyze the epidemiology, clinical features and costs of hospitalized patients with gout during the last decade in Spain. Retrospective observational study based on data from the Minimum Basic Data Set (MBDS) from the Spanish National Health Service database. Patients ≥ 18 years with any gout diagnosis at discharge who had been admitted to public or private hospitals between 2005 and 2015 were included. Patients were divided in two periods: p1 (2005–2010) and p2 (2011–2015) to compare the number of hospitalizations, mean costs and mortality rates. Data from 192,037 patients with gout was analyzed. There was an increase in the number of hospitalized patients with gout (p < 0.001). The more frequent comorbidities were diabetes (27.6% of patients), kidney disease (26.6%) and heart failure (19.3%). Liver disease (OR 2.61), dementia (OR 2.13), cerebrovascular diseases (OR 1.57), heart failure (OR 1.41), and kidney disease (OR 1.34) were associated with a higher mortality risk. Women had a lower risk of mortality than men (OR 0.85). General mortality rates in these hospitalized patients progressively increased over the years (p < 0.001). In addition, costs gradually rose, presenting a significant increase in p2 even after adjusting for inflation (p = 0.001). A progressive increase in hospitalizations, mortality rates and cost in hospitalized patients with gout was observed. This harmful trend in a preventable illness highlights the need for change and the search for new healthcare strategies.
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spelling pubmed-82257662021-07-02 Healthcare-related impact of gout in hospitalized patients in Spain Benavent, Diego Peiteado, Diana Martinez-Huedo, María Ángeles Hernandez-Hurtado, María Balsa, Alejandro de Miguel, Eugenio Sci Rep Article To analyze the epidemiology, clinical features and costs of hospitalized patients with gout during the last decade in Spain. Retrospective observational study based on data from the Minimum Basic Data Set (MBDS) from the Spanish National Health Service database. Patients ≥ 18 years with any gout diagnosis at discharge who had been admitted to public or private hospitals between 2005 and 2015 were included. Patients were divided in two periods: p1 (2005–2010) and p2 (2011–2015) to compare the number of hospitalizations, mean costs and mortality rates. Data from 192,037 patients with gout was analyzed. There was an increase in the number of hospitalized patients with gout (p < 0.001). The more frequent comorbidities were diabetes (27.6% of patients), kidney disease (26.6%) and heart failure (19.3%). Liver disease (OR 2.61), dementia (OR 2.13), cerebrovascular diseases (OR 1.57), heart failure (OR 1.41), and kidney disease (OR 1.34) were associated with a higher mortality risk. Women had a lower risk of mortality than men (OR 0.85). General mortality rates in these hospitalized patients progressively increased over the years (p < 0.001). In addition, costs gradually rose, presenting a significant increase in p2 even after adjusting for inflation (p = 0.001). A progressive increase in hospitalizations, mortality rates and cost in hospitalized patients with gout was observed. This harmful trend in a preventable illness highlights the need for change and the search for new healthcare strategies. Nature Publishing Group UK 2021-06-24 /pmc/articles/PMC8225766/ /pubmed/34168227 http://dx.doi.org/10.1038/s41598-021-92673-3 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Benavent, Diego
Peiteado, Diana
Martinez-Huedo, María Ángeles
Hernandez-Hurtado, María
Balsa, Alejandro
de Miguel, Eugenio
Healthcare-related impact of gout in hospitalized patients in Spain
title Healthcare-related impact of gout in hospitalized patients in Spain
title_full Healthcare-related impact of gout in hospitalized patients in Spain
title_fullStr Healthcare-related impact of gout in hospitalized patients in Spain
title_full_unstemmed Healthcare-related impact of gout in hospitalized patients in Spain
title_short Healthcare-related impact of gout in hospitalized patients in Spain
title_sort healthcare-related impact of gout in hospitalized patients in spain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225766/
https://www.ncbi.nlm.nih.gov/pubmed/34168227
http://dx.doi.org/10.1038/s41598-021-92673-3
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