Cargando…

The architecture of the SARS-CoV-2 RNA genome inside virion

SARS-CoV-2 carries the largest single-stranded RNA genome and is the causal pathogen of the ongoing COVID-19 pandemic. How the SARS-CoV-2 RNA genome is folded in the virion remains unknown. To fill the knowledge gap and facilitate structure-based drug development, we develop a virion RNA in situ con...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Changchang, Cai, Zhaokui, Xiao, Xia, Rao, Jian, Chen, Juan, Hu, Naijing, Yang, Minnan, Xing, Xiaorui, Wang, Yongle, Li, Manman, Zhou, Bing, Wang, Xiangxi, Wang, Jianwei, Xue, Yuanchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225788/ https://www.ncbi.nlm.nih.gov/pubmed/34168138 http://dx.doi.org/10.1038/s41467-021-22785-x

Ejemplares similares

Nanometer-resolution in situ structure of the SARS-CoV-2 postfusion spike protein
por: Tai, Linhua, et al.
Publicado: (2021)

Exploring the inside details of virions by electron microscopy
por: Liu, Zheng, et al.
Publicado: (2016)

CRIC-seq protocol for in situ profiling of proximal RNA-RNA contacts associated with RNA-binding proteins
por: Ye, Rong, et al.
Publicado: (2023)

Conserved and host-specific features of influenza virion architecture
por: Hutchinson, Edward C, et al.
Publicado: (2014)

Identification of a conserved virion-stabilizing network inside the interprotomer pocket of enteroviruses
por: Flatt, Justin W., et al.
Publicado: (2021)

Locations and in situ structure of the polymerase complex inside the virion of vesicular stomatitis virus
por: Si, Zhu, et al.
Publicado: (2022)

Localization of the Houdinisome (Ejection Proteins) inside the Bacteriophage P22 Virion by Bubblegram Imaging
por: Wu, Weimin, et al.
Publicado: (2016)

The RNA-binding protein ROD1/PTBP3 cotranscriptionally defines AID-loading sites to mediate antibody class switch in mammalian genomes
por: Chen, Juan, et al.
Publicado: (2018)

KRAS and VEGF gene 3'-UTR single nucleotide polymorphisms predicted susceptibility in colorectal cancer
por: Yang, Minnan, et al.
Publicado: (2017)

The encephalomyocarditis virus Leader promotes the release of virions inside extracellular vesicles via the induction of secretory autophagy
por: van der Grein, Susanne G., et al.
Publicado: (2022)

Inside Cisco IOS software architecture
por: Bollapragada, Vijay, et al.
Publicado: (2000)

Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation
por: Yang, Yunxiang, et al.
Publicado: (2020)

Packaging of viral RNAs in virions of adenoviruses
por: Xing, Li, et al.
Publicado: (2009)

Inside the machine: an illustrated introduction to microprocessors and computer architecture
por: Stokes, Jon
Publicado: (2007)

Virion Structure and Composition
por: Burrell, Christopher J., et al.
Publicado: (2017)

Antibody-Mediated Immobilization of Virions in Mucus
por: Jensen, Melanie A., et al.
Publicado: (2019)

Electron Tomography: Towards Visualizing Supramolecular Architecture Inside Cells
por: Baumeister, W., et al.
Publicado: (2002)

RF_phage virion: Classification of phage virion proteins with a random forest model
por: Zhang, Yanqin, et al.
Publicado: (2023)

Native Morphology of Influenza Virions
por: Noda, Takeshi
Publicado: (2012)

Corrigendum: RF_phage virion: classification of phage virion proteins with a random forest model
por: Zhang, Yanqin, et al.
Publicado: (2023)

Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms
por: Sun, Yao, et al.
Publicado: (2021)

Inside Java 2 platform security: architecture, API design, and implementation
por: Gong, Li, et al.
Publicado: (2004)

An Ensemble Method to Distinguish Bacteriophage Virion from Non-Virion Proteins Based on Protein Sequence Characteristics
por: Zhang, Lina, et al.
Publicado: (2015)

Morphogenesis of the Infectious HIV-1 Virion
por: Sakuragi, Jun-ichi
Publicado: (2011)

Histone Modifications in Papillomavirus Virion Minichromosomes
por: Porter, Samuel S., et al.
Publicado: (2021)

On the Sensitivity of the Virion Envelope to Lipid Peroxidation
por: Correa Sierra, Consuelo B., et al.
Publicado: (2022)

Inside outside : between architecture and landscape /
por: Berrizbeitia, Anita
Publicado: (1999)

SARS-CoV-2 Virion Stabilization by Zn Binding
por: Morante, Silvia, et al.
Publicado: (2020)

The total number and mass of SARS-CoV-2 virions
por: Sender, Ron, et al.
Publicado: (2021)

The total number and mass of SARS-CoV-2 virions
por: Sender, Ron, et al.
Publicado: (2021)

Profiling of cellular proteins in porcine reproductive and respiratory syndrome virus virions by proteomics analysis
por: Zhang, Chengwen, et al.
Publicado: (2010)

The E3 Ubiquitin Ligase RNF5 Facilitates SARS-CoV-2 Membrane Protein-Mediated Virion Release
por: Yuan, Zhen, et al.
Publicado: (2022)

Zika Virus NS2A-Mediated Virion Assembly
por: Zhang, Xianwen, et al.
Publicado: (2019)

Structural characteristics of the SARS-CoV-2 Omicron lineages BA.1 and BA.2 virions
por: Ma, Xiaoyu, et al.
Publicado: (2023)

Human Erythrocytes Selectively Bind and Enrich Infectious HIV-1 Virions
por: Beck, Zoltan, et al.
Publicado: (2009)

Finding new grain forms in three dimensions
por: Wang, Hao, et al.
Publicado: (2019)

Structural Dynamics of Bacteriophage P22 Virions During the Initiation of Infection
por: Wang, Chunyan, et al.
Publicado: (2019)

Influenza A Virus Cell Entry, Replication, Virion Assembly and Movement
por: Dou, Dan, et al.
Publicado: (2018)

Proteomic analysis of the EhV-86 virion
por: Allen, Michael J, et al.
Publicado: (2008)

A Rondelay (Without Cadenza) By The Virion Of Influenza
por: Kilbourne, Edwin D.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_bspqf5d7ciohnrh3e72ir96l42