A mouse model of prenatal exposure to Interleukin-6 to study the developmental origin of health and disease

Systemic inflammation in pregnant obese women is associated with 1.5- to 2-fold increase in serum Interleukin-6 (IL-6) and newborns with lower kidney/body weight ratio but the role of IL-6 in increased susceptibility to chronic kidney (CKD) in adult progeny is not known. Since IL-6 crosses the place...

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Detalles Bibliográficos
Autores principales: Srivastava, Tarak, Joshi, Trupti, Heruth, Daniel P., Rezaiekhaligh, Mohammad H., Garola, Robert E., Zhou, Jianping, Boinpelly, Varun C., Ali, Mohammed Farhan, Alon, Uri S., Sharma, Madhulika, Vanden Heuvel, Gregory B., Mahajan, Pramod, Priya, Lakshmi, Jiang, Yuexu, McCarthy, Ellen T., Savin, Virginia J., Sharma, Ram, Sharma, Mukut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225793/
https://www.ncbi.nlm.nih.gov/pubmed/34168254
http://dx.doi.org/10.1038/s41598-021-92751-6

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