Whole-exome sequencing of alpha-fetoprotein producing gastric carcinoma reveals genomic profile and therapeutic targets

Alpha-fetoprotein producing gastric carcinoma (AFPGC) is a rare and aggressive subtype of gastric cancer. However, little is known about the genomic features of this disease. We perform whole-exome sequencing analysis of AFPGC, and identify 34 significantly mutated genes. Somatic copy number alterat...

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Detalles Bibliográficos
Autores principales: Lu, Jun, Ding, Yongfeng, Chen, Yanyan, Jiang, Junjie, Chen, Yiran, Huang, Yingying, Wu, Mengjie, Li, Chengzhi, Kong, Mei, Zhao, Wenyi, Wang, Haohao, Zhang, Jing, Li, Zhongqi, Lu, Yimin, Yu, Xiongfei, Jin, Ketao, Zhou, Donghui, Zhou, Tianhua, Teng, Fei, Zhang, Haibin, Zhou, Zhan, Wang, Haiyong, Teng, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225795/
https://www.ncbi.nlm.nih.gov/pubmed/34168152
http://dx.doi.org/10.1038/s41467-021-24170-0

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