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Effect of multidisciplinary team care on survival of oesophageal cancer patients: a retrospective nationwide cohort study

Oesophageal cancer is the sixth leading cause of cancer death worldwide. This nationwide study analyses the survival results of oesophageal cancer under multidisciplinary team (MDT) care. We enrolled oesophageal cancer patients diagnosed between 2010 and 2015 with follow-up for at least 1 year. This...

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Autores principales: Huang, Yuan-Chun, Kung, Pei-Tseng, Ho, Shang-Yun, Tyan, Yeu-Sheng, Chiu, Li-Ting, Tsai, Wen-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225808/
https://www.ncbi.nlm.nih.gov/pubmed/34168186
http://dx.doi.org/10.1038/s41598-021-92618-w
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author Huang, Yuan-Chun
Kung, Pei-Tseng
Ho, Shang-Yun
Tyan, Yeu-Sheng
Chiu, Li-Ting
Tsai, Wen-Chen
author_facet Huang, Yuan-Chun
Kung, Pei-Tseng
Ho, Shang-Yun
Tyan, Yeu-Sheng
Chiu, Li-Ting
Tsai, Wen-Chen
author_sort Huang, Yuan-Chun
collection PubMed
description Oesophageal cancer is the sixth leading cause of cancer death worldwide. This nationwide study analyses the survival results of oesophageal cancer under multidisciplinary team (MDT) care. We enrolled oesophageal cancer patients diagnosed between 2010 and 2015 with follow-up for at least 1 year. This study performed propensity score matching with a ratio of 1:1 between MDT participants and non-MDT participants. We performed conditional Cox proportional hazards model to research relative risk of survival and associated factors of survival. The adjusted survival curves were plotted. 8184 newly diagnosed oesophageal cancer patients were included. The favourable survival factors include participant status of MDT, gender, monthly salary, urbanization level, other catastrophic illness, stage of cancer, treatment methods, and service volume of physicians (P < 0.05). MDT participants showed lower risk of death (HR = 0.73; 95% CI 0.67–0.79). Further stratification analysis revealed that the incorporation of an MDT reduced the death risk of patients with stages 2, 3, and 4 cancer, with the greatest reduction observed in patients with stage 3 cancer (HR = 0.72; 95% CI 0.67–0.79). The risk of death was lower for oesophageal cancer patients who enrolled in MDT care.
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spelling pubmed-82258082021-07-02 Effect of multidisciplinary team care on survival of oesophageal cancer patients: a retrospective nationwide cohort study Huang, Yuan-Chun Kung, Pei-Tseng Ho, Shang-Yun Tyan, Yeu-Sheng Chiu, Li-Ting Tsai, Wen-Chen Sci Rep Article Oesophageal cancer is the sixth leading cause of cancer death worldwide. This nationwide study analyses the survival results of oesophageal cancer under multidisciplinary team (MDT) care. We enrolled oesophageal cancer patients diagnosed between 2010 and 2015 with follow-up for at least 1 year. This study performed propensity score matching with a ratio of 1:1 between MDT participants and non-MDT participants. We performed conditional Cox proportional hazards model to research relative risk of survival and associated factors of survival. The adjusted survival curves were plotted. 8184 newly diagnosed oesophageal cancer patients were included. The favourable survival factors include participant status of MDT, gender, monthly salary, urbanization level, other catastrophic illness, stage of cancer, treatment methods, and service volume of physicians (P < 0.05). MDT participants showed lower risk of death (HR = 0.73; 95% CI 0.67–0.79). Further stratification analysis revealed that the incorporation of an MDT reduced the death risk of patients with stages 2, 3, and 4 cancer, with the greatest reduction observed in patients with stage 3 cancer (HR = 0.72; 95% CI 0.67–0.79). The risk of death was lower for oesophageal cancer patients who enrolled in MDT care. Nature Publishing Group UK 2021-06-24 /pmc/articles/PMC8225808/ /pubmed/34168186 http://dx.doi.org/10.1038/s41598-021-92618-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Huang, Yuan-Chun
Kung, Pei-Tseng
Ho, Shang-Yun
Tyan, Yeu-Sheng
Chiu, Li-Ting
Tsai, Wen-Chen
Effect of multidisciplinary team care on survival of oesophageal cancer patients: a retrospective nationwide cohort study
title Effect of multidisciplinary team care on survival of oesophageal cancer patients: a retrospective nationwide cohort study
title_full Effect of multidisciplinary team care on survival of oesophageal cancer patients: a retrospective nationwide cohort study
title_fullStr Effect of multidisciplinary team care on survival of oesophageal cancer patients: a retrospective nationwide cohort study
title_full_unstemmed Effect of multidisciplinary team care on survival of oesophageal cancer patients: a retrospective nationwide cohort study
title_short Effect of multidisciplinary team care on survival of oesophageal cancer patients: a retrospective nationwide cohort study
title_sort effect of multidisciplinary team care on survival of oesophageal cancer patients: a retrospective nationwide cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225808/
https://www.ncbi.nlm.nih.gov/pubmed/34168186
http://dx.doi.org/10.1038/s41598-021-92618-w
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