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Integrated lipidomics and proteomics reveal cardiolipin alterations, upregulation of HADHA and long chain fatty acids in pancreatic cancer stem cells

Pancreatic cancer stem cells (PCSCs) play a key role in the aggressiveness of pancreatic ductal adenocarcinomas (PDAC); however, little is known about their signaling and metabolic pathways. Here we show that PCSCs have specific and common proteome and lipidome modulations. PCSCs displayed downregul...

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Detalles Bibliográficos
Autores principales:	Di Carlo, Claudia, Sousa, Bebiana C., Manfredi, Marcello, Brandi, Jessica, Dalla Pozza, Elisa, Marengo, Emilio, Palmieri, Marta, Dando, Ilaria, Wakelam, Michael J. O., Lopez-Clavijo, Andrea F., Cecconi, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225828/ https://www.ncbi.nlm.nih.gov/pubmed/34168259 http://dx.doi.org/10.1038/s41598-021-92752-5

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