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Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers

Tinnitus can be a burdensome condition on both individual and societal levels. Many aspects of this condition remain elusive, including its underlying mechanisms, ultimately hindering the development of a cure. Interdisciplinary approaches are required to overcome long-established research challenge...

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Autores principales: Simoes, Jorge Piano, Daoud, Elza, Shabbir, Maryam, Amanat, Sana, Assouly, Kelly, Biswas, Roshni, Casolani, Chiara, Dode, Albi, Enzler, Falco, Jacquemin, Laure, Joergensen, Mie, Kok, Tori, Liyanage, Nuwan, Lourenco, Matheus, Makani, Punitkumar, Mehdi, Muntazir, Ramadhani, Anissa L., Riha, Constanze, Santacruz, Jose Lopez, Schiller, Axel, Schoisswohl, Stefan, Trpchevska, Natalia, Genitsaridi, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225955/
https://www.ncbi.nlm.nih.gov/pubmed/34177549
http://dx.doi.org/10.3389/fnagi.2021.647285
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author Simoes, Jorge Piano
Daoud, Elza
Shabbir, Maryam
Amanat, Sana
Assouly, Kelly
Biswas, Roshni
Casolani, Chiara
Dode, Albi
Enzler, Falco
Jacquemin, Laure
Joergensen, Mie
Kok, Tori
Liyanage, Nuwan
Lourenco, Matheus
Makani, Punitkumar
Mehdi, Muntazir
Ramadhani, Anissa L.
Riha, Constanze
Santacruz, Jose Lopez
Schiller, Axel
Schoisswohl, Stefan
Trpchevska, Natalia
Genitsaridi, Eleni
author_facet Simoes, Jorge Piano
Daoud, Elza
Shabbir, Maryam
Amanat, Sana
Assouly, Kelly
Biswas, Roshni
Casolani, Chiara
Dode, Albi
Enzler, Falco
Jacquemin, Laure
Joergensen, Mie
Kok, Tori
Liyanage, Nuwan
Lourenco, Matheus
Makani, Punitkumar
Mehdi, Muntazir
Ramadhani, Anissa L.
Riha, Constanze
Santacruz, Jose Lopez
Schiller, Axel
Schoisswohl, Stefan
Trpchevska, Natalia
Genitsaridi, Eleni
author_sort Simoes, Jorge Piano
collection PubMed
description Tinnitus can be a burdensome condition on both individual and societal levels. Many aspects of this condition remain elusive, including its underlying mechanisms, ultimately hindering the development of a cure. Interdisciplinary approaches are required to overcome long-established research challenges. This review summarizes current knowledge in various tinnitus-relevant research fields including tinnitus generating mechanisms, heterogeneity, epidemiology, assessment, and treatment development, in an effort to highlight the main challenges and provide suggestions for future research to overcome them. Four common themes across different areas were identified as future research direction: (1) Further establishment of multicenter and multidisciplinary collaborations; (2) Systematic reviews and syntheses of existing knowledge; (3) Standardization of research methods including tinnitus assessment, data acquisition, and data analysis protocols; (4) The design of studies with large sample sizes and the creation of large tinnitus-specific databases that would allow in-depth exploration of tinnitus heterogeneity.
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spelling pubmed-82259552021-06-26 Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers Simoes, Jorge Piano Daoud, Elza Shabbir, Maryam Amanat, Sana Assouly, Kelly Biswas, Roshni Casolani, Chiara Dode, Albi Enzler, Falco Jacquemin, Laure Joergensen, Mie Kok, Tori Liyanage, Nuwan Lourenco, Matheus Makani, Punitkumar Mehdi, Muntazir Ramadhani, Anissa L. Riha, Constanze Santacruz, Jose Lopez Schiller, Axel Schoisswohl, Stefan Trpchevska, Natalia Genitsaridi, Eleni Front Aging Neurosci Neuroscience Tinnitus can be a burdensome condition on both individual and societal levels. Many aspects of this condition remain elusive, including its underlying mechanisms, ultimately hindering the development of a cure. Interdisciplinary approaches are required to overcome long-established research challenges. This review summarizes current knowledge in various tinnitus-relevant research fields including tinnitus generating mechanisms, heterogeneity, epidemiology, assessment, and treatment development, in an effort to highlight the main challenges and provide suggestions for future research to overcome them. Four common themes across different areas were identified as future research direction: (1) Further establishment of multicenter and multidisciplinary collaborations; (2) Systematic reviews and syntheses of existing knowledge; (3) Standardization of research methods including tinnitus assessment, data acquisition, and data analysis protocols; (4) The design of studies with large sample sizes and the creation of large tinnitus-specific databases that would allow in-depth exploration of tinnitus heterogeneity. Frontiers Media S.A. 2021-06-11 /pmc/articles/PMC8225955/ /pubmed/34177549 http://dx.doi.org/10.3389/fnagi.2021.647285 Text en Copyright © 2021 Simoes, Daoud, Shabbir, Amanat, Assouly, Biswas, Casolani, Dode, Enzler, Jacquemin, Joergensen, Kok, Liyanage, Lourenco, Makani, Mehdi, Ramadhani, Riha, Santacruz, Schiller, Schoisswohl, Trpchevska and Genitsaridi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Simoes, Jorge Piano
Daoud, Elza
Shabbir, Maryam
Amanat, Sana
Assouly, Kelly
Biswas, Roshni
Casolani, Chiara
Dode, Albi
Enzler, Falco
Jacquemin, Laure
Joergensen, Mie
Kok, Tori
Liyanage, Nuwan
Lourenco, Matheus
Makani, Punitkumar
Mehdi, Muntazir
Ramadhani, Anissa L.
Riha, Constanze
Santacruz, Jose Lopez
Schiller, Axel
Schoisswohl, Stefan
Trpchevska, Natalia
Genitsaridi, Eleni
Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers
title Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers
title_full Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers
title_fullStr Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers
title_full_unstemmed Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers
title_short Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers
title_sort multidisciplinary tinnitus research: challenges and future directions from the perspective of early stage researchers
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225955/
https://www.ncbi.nlm.nih.gov/pubmed/34177549
http://dx.doi.org/10.3389/fnagi.2021.647285
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