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Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers
Tinnitus can be a burdensome condition on both individual and societal levels. Many aspects of this condition remain elusive, including its underlying mechanisms, ultimately hindering the development of a cure. Interdisciplinary approaches are required to overcome long-established research challenge...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225955/ https://www.ncbi.nlm.nih.gov/pubmed/34177549 http://dx.doi.org/10.3389/fnagi.2021.647285 |
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author | Simoes, Jorge Piano Daoud, Elza Shabbir, Maryam Amanat, Sana Assouly, Kelly Biswas, Roshni Casolani, Chiara Dode, Albi Enzler, Falco Jacquemin, Laure Joergensen, Mie Kok, Tori Liyanage, Nuwan Lourenco, Matheus Makani, Punitkumar Mehdi, Muntazir Ramadhani, Anissa L. Riha, Constanze Santacruz, Jose Lopez Schiller, Axel Schoisswohl, Stefan Trpchevska, Natalia Genitsaridi, Eleni |
author_facet | Simoes, Jorge Piano Daoud, Elza Shabbir, Maryam Amanat, Sana Assouly, Kelly Biswas, Roshni Casolani, Chiara Dode, Albi Enzler, Falco Jacquemin, Laure Joergensen, Mie Kok, Tori Liyanage, Nuwan Lourenco, Matheus Makani, Punitkumar Mehdi, Muntazir Ramadhani, Anissa L. Riha, Constanze Santacruz, Jose Lopez Schiller, Axel Schoisswohl, Stefan Trpchevska, Natalia Genitsaridi, Eleni |
author_sort | Simoes, Jorge Piano |
collection | PubMed |
description | Tinnitus can be a burdensome condition on both individual and societal levels. Many aspects of this condition remain elusive, including its underlying mechanisms, ultimately hindering the development of a cure. Interdisciplinary approaches are required to overcome long-established research challenges. This review summarizes current knowledge in various tinnitus-relevant research fields including tinnitus generating mechanisms, heterogeneity, epidemiology, assessment, and treatment development, in an effort to highlight the main challenges and provide suggestions for future research to overcome them. Four common themes across different areas were identified as future research direction: (1) Further establishment of multicenter and multidisciplinary collaborations; (2) Systematic reviews and syntheses of existing knowledge; (3) Standardization of research methods including tinnitus assessment, data acquisition, and data analysis protocols; (4) The design of studies with large sample sizes and the creation of large tinnitus-specific databases that would allow in-depth exploration of tinnitus heterogeneity. |
format | Online Article Text |
id | pubmed-8225955 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82259552021-06-26 Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers Simoes, Jorge Piano Daoud, Elza Shabbir, Maryam Amanat, Sana Assouly, Kelly Biswas, Roshni Casolani, Chiara Dode, Albi Enzler, Falco Jacquemin, Laure Joergensen, Mie Kok, Tori Liyanage, Nuwan Lourenco, Matheus Makani, Punitkumar Mehdi, Muntazir Ramadhani, Anissa L. Riha, Constanze Santacruz, Jose Lopez Schiller, Axel Schoisswohl, Stefan Trpchevska, Natalia Genitsaridi, Eleni Front Aging Neurosci Neuroscience Tinnitus can be a burdensome condition on both individual and societal levels. Many aspects of this condition remain elusive, including its underlying mechanisms, ultimately hindering the development of a cure. Interdisciplinary approaches are required to overcome long-established research challenges. This review summarizes current knowledge in various tinnitus-relevant research fields including tinnitus generating mechanisms, heterogeneity, epidemiology, assessment, and treatment development, in an effort to highlight the main challenges and provide suggestions for future research to overcome them. Four common themes across different areas were identified as future research direction: (1) Further establishment of multicenter and multidisciplinary collaborations; (2) Systematic reviews and syntheses of existing knowledge; (3) Standardization of research methods including tinnitus assessment, data acquisition, and data analysis protocols; (4) The design of studies with large sample sizes and the creation of large tinnitus-specific databases that would allow in-depth exploration of tinnitus heterogeneity. Frontiers Media S.A. 2021-06-11 /pmc/articles/PMC8225955/ /pubmed/34177549 http://dx.doi.org/10.3389/fnagi.2021.647285 Text en Copyright © 2021 Simoes, Daoud, Shabbir, Amanat, Assouly, Biswas, Casolani, Dode, Enzler, Jacquemin, Joergensen, Kok, Liyanage, Lourenco, Makani, Mehdi, Ramadhani, Riha, Santacruz, Schiller, Schoisswohl, Trpchevska and Genitsaridi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Simoes, Jorge Piano Daoud, Elza Shabbir, Maryam Amanat, Sana Assouly, Kelly Biswas, Roshni Casolani, Chiara Dode, Albi Enzler, Falco Jacquemin, Laure Joergensen, Mie Kok, Tori Liyanage, Nuwan Lourenco, Matheus Makani, Punitkumar Mehdi, Muntazir Ramadhani, Anissa L. Riha, Constanze Santacruz, Jose Lopez Schiller, Axel Schoisswohl, Stefan Trpchevska, Natalia Genitsaridi, Eleni Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers |
title | Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers |
title_full | Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers |
title_fullStr | Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers |
title_full_unstemmed | Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers |
title_short | Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers |
title_sort | multidisciplinary tinnitus research: challenges and future directions from the perspective of early stage researchers |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8225955/ https://www.ncbi.nlm.nih.gov/pubmed/34177549 http://dx.doi.org/10.3389/fnagi.2021.647285 |
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