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Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration
The knowledge about how different subsystems participate and interplay in sensorimotor control is fundamental to understand motor deficits associated with CNS injury and movement recovery. The role of corticospinal (CS) and rubrospinal (RS) projections in motor control has been extensively studied a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226017/ https://www.ncbi.nlm.nih.gov/pubmed/34177458 http://dx.doi.org/10.3389/fnins.2021.686481 |
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author | Olivares-Moreno, Rafael Rodriguez-Moreno, Paola Lopez-Virgen, Veronica Macías, Martín Altamira-Camacho, Moisés Rojas-Piloni, Gerardo |
author_facet | Olivares-Moreno, Rafael Rodriguez-Moreno, Paola Lopez-Virgen, Veronica Macías, Martín Altamira-Camacho, Moisés Rojas-Piloni, Gerardo |
author_sort | Olivares-Moreno, Rafael |
collection | PubMed |
description | The knowledge about how different subsystems participate and interplay in sensorimotor control is fundamental to understand motor deficits associated with CNS injury and movement recovery. The role of corticospinal (CS) and rubrospinal (RS) projections in motor control has been extensively studied and compared, and it is clear that both systems are important for skilled movement. However, during phylogeny, the emerging cerebral cortex took a higher hierarchical role controlling rubro-cerebellar circuits. Here, we present anatomical, neurophysiological, and behavioral evidence suggesting that both systems modulate complex segmental neuronal networks in a parallel way, which is important for sensorimotor integration at spinal cord level. We also highlight that, although specializations exist, both systems could be complementary and potentially subserve motor recovery associated with CNS damage. |
format | Online Article Text |
id | pubmed-8226017 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82260172021-06-26 Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration Olivares-Moreno, Rafael Rodriguez-Moreno, Paola Lopez-Virgen, Veronica Macías, Martín Altamira-Camacho, Moisés Rojas-Piloni, Gerardo Front Neurosci Neuroscience The knowledge about how different subsystems participate and interplay in sensorimotor control is fundamental to understand motor deficits associated with CNS injury and movement recovery. The role of corticospinal (CS) and rubrospinal (RS) projections in motor control has been extensively studied and compared, and it is clear that both systems are important for skilled movement. However, during phylogeny, the emerging cerebral cortex took a higher hierarchical role controlling rubro-cerebellar circuits. Here, we present anatomical, neurophysiological, and behavioral evidence suggesting that both systems modulate complex segmental neuronal networks in a parallel way, which is important for sensorimotor integration at spinal cord level. We also highlight that, although specializations exist, both systems could be complementary and potentially subserve motor recovery associated with CNS damage. Frontiers Media S.A. 2021-06-11 /pmc/articles/PMC8226017/ /pubmed/34177458 http://dx.doi.org/10.3389/fnins.2021.686481 Text en Copyright © 2021 Olivares-Moreno, Rodriguez-Moreno, Lopez-Virgen, Macías, Altamira-Camacho and Rojas-Piloni. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Olivares-Moreno, Rafael Rodriguez-Moreno, Paola Lopez-Virgen, Veronica Macías, Martín Altamira-Camacho, Moisés Rojas-Piloni, Gerardo Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration |
title | Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration |
title_full | Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration |
title_fullStr | Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration |
title_full_unstemmed | Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration |
title_short | Corticospinal vs Rubrospinal Revisited: An Evolutionary Perspective for Sensorimotor Integration |
title_sort | corticospinal vs rubrospinal revisited: an evolutionary perspective for sensorimotor integration |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226017/ https://www.ncbi.nlm.nih.gov/pubmed/34177458 http://dx.doi.org/10.3389/fnins.2021.686481 |
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