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EGFR and PI3K Pathway Activities Might Guide Drug Repurposing in HPV-Negative Head and Neck Cancers

While genetic alterations in Epidermal growth factor receptor (EGFR) and PI3K are common in head and neck squamous cell carcinomas (HNSCC), their impact on oncogenic signaling and cancer drug sensitivities remains elusive. To determine their consequences on the transcriptional network, pathway activ...

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Detalles Bibliográficos
Autores principales:	Mock, Andreas, Plath, Michaela, Moratin, Julius, Tapken, Maria Johanna, Jäger, Dirk, Krauss, Jürgen, Fröhling, Stefan, Hess, Jochen, Zaoui, Karim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226088/ https://www.ncbi.nlm.nih.gov/pubmed/34178665 http://dx.doi.org/10.3389/fonc.2021.678966

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