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Polydatin Reduces Cardiotoxicity and Enhances the Anticancer Effects of Sunitinib by Decreasing Pro-Oxidative Stress, Pro-Inflammatory Cytokines, and NLRP3 Inflammasome Expression

Renal cell carcinoma (RCC) represents the main renal tumors and are highly metastatic. Sunitinib, a recently-approved, multi-targeted Tyrosine Kinases Inhibitor (TKi), prolongs survival in patients with metastatic renal cell carcinoma and gastrointestinal stromal tumors, however a dose related cardi...

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Detalles Bibliográficos
Autores principales:	Quagliariello, Vincenzo, Berretta, Massimiliano, Buccolo, Simona, Iovine, Martina, Paccone, Andrea, Cavalcanti, Ernesta, Taibi, Rosaria, Montopoli, Monica, Botti, Gerardo, Maurea, Nicola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226180/ https://www.ncbi.nlm.nih.gov/pubmed/34178667 http://dx.doi.org/10.3389/fonc.2021.680758

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