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Heterogeneous Streptomycin Resistance Level Among Mycobacterium tuberculosis Strains From the Same Transmission Cluster

Widespread and frequent resistance to the second-line tuberculosis (TB) medicine streptomycin, suggests ongoing transmission of low fitness cost streptomycin resistance mutations. To investigate this hypothesis, we studied a cohort of 681 individuals from a TB epidemic in Portugal. Whole-genome sequ...

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Detalles Bibliográficos
Autores principales:	Rocha, Deisy M. G. C., Magalhães, Carlos, Cá, Baltazar, Ramos, Angelica, Carvalho, Teresa, Comas, Iñaki, Guimarães, João Tiago, Bastos, Helder Novais, Saraiva, Margarida, Osório, Nuno S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226182/ https://www.ncbi.nlm.nih.gov/pubmed/34177837 http://dx.doi.org/10.3389/fmicb.2021.659545

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