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Identification of Somatic Genetic Alterations Using Whole-Exome Sequencing of Uterine Leiomyosarcoma Tumors

BACKGROUND: The genomic abnormalities associated with uterine leiomyosarcoma (uLMS) have not been fully elucidated to date. OBJECTIVE: To understand the pathogenesis of uLMS and to identify driver mutations and potential therapeutic targets in uLMS. METHODS: Three matched tumor-constitutional DNA pa...

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Detalles Bibliográficos
Autores principales:	Chen, Lihua, Li, Jiajia, Wu, Xiaohua, Zheng, Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226214/ https://www.ncbi.nlm.nih.gov/pubmed/34178683 http://dx.doi.org/10.3389/fonc.2021.687899

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