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Meta-Assessment of Metformin Absorption and Disposition Pharmacokinetics in Nine Species

The objective of this study was to systematically assess literature datasets and quantitatively analyze metformin PK in plasma and some tissues of nine species. The pharmacokinetic (PK) parameters and profiles of metformin in nine species were collected from the literature. Based on a simple allomet...

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Detalles Bibliográficos
Autores principales: Jeong, Yoo-Seong, Jusko, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226464/
https://www.ncbi.nlm.nih.gov/pubmed/34200427
http://dx.doi.org/10.3390/ph14060545