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A Pulmonary Pleomorphic Carcinoma Patient with Exudative Retinal Detachment Secondary to Choroid Metastasis as Initial Presentation—A Case Report

Choroid metastasis is the initial presentation of pleomorphic carcinoma (PC) of the lung. PC is classified as poorly differentiated non-small cell lung carcinoma. It has a tendency to metastasize early and has a poor response to chemotherapy, which often results in poor prognosis. We report the case...

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Autores principales: Feng, Kathy-Ming, Chen, Yi-Hao, Chen, Jiann-Torng, Lin, Li-Fan, Tsai, Wen-Chiuan, Chen, Ching-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226557/
https://www.ncbi.nlm.nih.gov/pubmed/34071184
http://dx.doi.org/10.3390/medicina57060539
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author Feng, Kathy-Ming
Chen, Yi-Hao
Chen, Jiann-Torng
Lin, Li-Fan
Tsai, Wen-Chiuan
Chen, Ching-Long
author_facet Feng, Kathy-Ming
Chen, Yi-Hao
Chen, Jiann-Torng
Lin, Li-Fan
Tsai, Wen-Chiuan
Chen, Ching-Long
author_sort Feng, Kathy-Ming
collection PubMed
description Choroid metastasis is the initial presentation of pleomorphic carcinoma (PC) of the lung. PC is classified as poorly differentiated non-small cell lung carcinoma. It has a tendency to metastasize early and has a poor response to chemotherapy, which often results in poor prognosis. We report the case of a 63-year-old woman with a one-month history of deteriorating vision in the left eye. Fundus examination, fluorescein angiography, indocyanine green angiography, and B-scan sonography demonstrated choroidal metastasis of the left eye. Positron emission tomography/computed tomography (PET/CT) revealed a tumor with increased uptake in the left upper lung. Subsequent bronchoscopic biopsy confirmed a pleomorphic carcinoma of the lungs. Choroid metastasis as an initial presentation of PC in the lung is rare. Usually, it represents the late course of disseminated disease with hematogenous spread. Prompt diagnosis is imperative for patients to immediately initiate treatment.
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spelling pubmed-82265572021-06-26 A Pulmonary Pleomorphic Carcinoma Patient with Exudative Retinal Detachment Secondary to Choroid Metastasis as Initial Presentation—A Case Report Feng, Kathy-Ming Chen, Yi-Hao Chen, Jiann-Torng Lin, Li-Fan Tsai, Wen-Chiuan Chen, Ching-Long Medicina (Kaunas) Case Report Choroid metastasis is the initial presentation of pleomorphic carcinoma (PC) of the lung. PC is classified as poorly differentiated non-small cell lung carcinoma. It has a tendency to metastasize early and has a poor response to chemotherapy, which often results in poor prognosis. We report the case of a 63-year-old woman with a one-month history of deteriorating vision in the left eye. Fundus examination, fluorescein angiography, indocyanine green angiography, and B-scan sonography demonstrated choroidal metastasis of the left eye. Positron emission tomography/computed tomography (PET/CT) revealed a tumor with increased uptake in the left upper lung. Subsequent bronchoscopic biopsy confirmed a pleomorphic carcinoma of the lungs. Choroid metastasis as an initial presentation of PC in the lung is rare. Usually, it represents the late course of disseminated disease with hematogenous spread. Prompt diagnosis is imperative for patients to immediately initiate treatment. MDPI 2021-05-28 /pmc/articles/PMC8226557/ /pubmed/34071184 http://dx.doi.org/10.3390/medicina57060539 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Feng, Kathy-Ming
Chen, Yi-Hao
Chen, Jiann-Torng
Lin, Li-Fan
Tsai, Wen-Chiuan
Chen, Ching-Long
A Pulmonary Pleomorphic Carcinoma Patient with Exudative Retinal Detachment Secondary to Choroid Metastasis as Initial Presentation—A Case Report
title A Pulmonary Pleomorphic Carcinoma Patient with Exudative Retinal Detachment Secondary to Choroid Metastasis as Initial Presentation—A Case Report
title_full A Pulmonary Pleomorphic Carcinoma Patient with Exudative Retinal Detachment Secondary to Choroid Metastasis as Initial Presentation—A Case Report
title_fullStr A Pulmonary Pleomorphic Carcinoma Patient with Exudative Retinal Detachment Secondary to Choroid Metastasis as Initial Presentation—A Case Report
title_full_unstemmed A Pulmonary Pleomorphic Carcinoma Patient with Exudative Retinal Detachment Secondary to Choroid Metastasis as Initial Presentation—A Case Report
title_short A Pulmonary Pleomorphic Carcinoma Patient with Exudative Retinal Detachment Secondary to Choroid Metastasis as Initial Presentation—A Case Report
title_sort pulmonary pleomorphic carcinoma patient with exudative retinal detachment secondary to choroid metastasis as initial presentation—a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226557/
https://www.ncbi.nlm.nih.gov/pubmed/34071184
http://dx.doi.org/10.3390/medicina57060539
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