Molecular Genetics in Neuroblastoma Prognosis

In recent years, much research has been carried out to identify the biological and genetic characteristics of the neuroblastoma (NB) tumor in order to precisely define the prognostic subgroups for improving treatment stratification. This review will describe the major genetic features and the recent...

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Autores principales: Lerone, Margherita, Ognibene, Marzia, Pezzolo, Annalisa, Martucciello, Giuseppe, Zara, Federico, Morini, Martina, Mazzocco, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226597/
https://www.ncbi.nlm.nih.gov/pubmed/34072462
http://dx.doi.org/10.3390/children8060456
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author Lerone, Margherita
Ognibene, Marzia
Pezzolo, Annalisa
Martucciello, Giuseppe
Zara, Federico
Morini, Martina
Mazzocco, Katia
author_facet Lerone, Margherita
Ognibene, Marzia
Pezzolo, Annalisa
Martucciello, Giuseppe
Zara, Federico
Morini, Martina
Mazzocco, Katia
author_sort Lerone, Margherita
collection PubMed
description In recent years, much research has been carried out to identify the biological and genetic characteristics of the neuroblastoma (NB) tumor in order to precisely define the prognostic subgroups for improving treatment stratification. This review will describe the major genetic features and the recent scientific advances, focusing on their impact on diagnosis, prognosis, and therapeutic solutions in NB clinical management.
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spelling pubmed-82265972021-06-26 Molecular Genetics in Neuroblastoma Prognosis Lerone, Margherita Ognibene, Marzia Pezzolo, Annalisa Martucciello, Giuseppe Zara, Federico Morini, Martina Mazzocco, Katia Children (Basel) Review In recent years, much research has been carried out to identify the biological and genetic characteristics of the neuroblastoma (NB) tumor in order to precisely define the prognostic subgroups for improving treatment stratification. This review will describe the major genetic features and the recent scientific advances, focusing on their impact on diagnosis, prognosis, and therapeutic solutions in NB clinical management. MDPI 2021-05-29 /pmc/articles/PMC8226597/ /pubmed/34072462 http://dx.doi.org/10.3390/children8060456 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lerone, Margherita
Ognibene, Marzia
Pezzolo, Annalisa
Martucciello, Giuseppe
Zara, Federico
Morini, Martina
Mazzocco, Katia
Molecular Genetics in Neuroblastoma Prognosis
title Molecular Genetics in Neuroblastoma Prognosis
title_full Molecular Genetics in Neuroblastoma Prognosis
title_fullStr Molecular Genetics in Neuroblastoma Prognosis
title_full_unstemmed Molecular Genetics in Neuroblastoma Prognosis
title_short Molecular Genetics in Neuroblastoma Prognosis
title_sort molecular genetics in neuroblastoma prognosis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226597/
https://www.ncbi.nlm.nih.gov/pubmed/34072462
http://dx.doi.org/10.3390/children8060456
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