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Profiling Dopamine-Induced Oxidized Proteoforms of β-synuclein by Top-Down Mass Spectrometry

The formation of multiple proteoforms by post-translational modifications (PTMs) enables a single protein to acquire distinct functional roles in its biological context. Oxidation of methionine residues (Met) is a common PTM, involved in physiological (e.g., signaling) and pathological (e.g., oxidat...

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Detalles Bibliográficos
Autores principales: Luise, Arianna, De Cecco, Elena, Ponzini, Erika, Sollazzo, Martina, Mauri, PierLuigi, Sobott, Frank, Legname, Giuseppe, Grandori, Rita, Santambrogio, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226665/
https://www.ncbi.nlm.nih.gov/pubmed/34206096
http://dx.doi.org/10.3390/antiox10060893