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Comparison of Transcriptomic Profiles of MiaPaCa-2 Pancreatic Cancer Cells Treated with Different Statins

Statins have been widely used for the treatment of hypercholesterolemia due to their ability to inhibit HMG-CoA reductase, the rate-limiting enzyme of de novo cholesterol synthesis, via the so-called mevalonate pathway. However, their inhibitory action also causes depletion of downstream intermediat...

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Detalles Bibliográficos
Autores principales:	Rimpelová, Silvie, Kolář, Michal, Strnad, Hynek, Ruml, Tomáš, Vítek, Libor, Gbelcová, Helena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226792/ https://www.ncbi.nlm.nih.gov/pubmed/34207840 http://dx.doi.org/10.3390/molecules26123528

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