Impaired Right Ventricular Calcium Cycling Is an Early Risk Factor in R14del-Phospholamban Arrhythmias

The inherited mutation (R14del) in the calcium regulatory protein phospholamban (PLN) is linked to malignant ventricular arrhythmia with poor prognosis starting at adolescence. However, the underlying early mechanisms that may serve as prognostic factors remain elusive. This study generated humanize...

Descripción completa

Detalles Bibliográficos
Autores principales: Haghighi, Kobra, Gardner, George, Vafiadaki, Elizabeth, Kumar, Mohit, Green, Lisa C., Ma, Jianyong, Crocker, Jeffrey S., Koch, Sheryl, Arvanitis, Demetrios A., Bidwell, Phillip, Rubinstein, Jack, van de Leur, Rutger, Doevendans, Pieter A., Akar, Fadi G., Tranter, Michael, Wang, Hong-Sheng, Sadayappan, Sakthivel, DeMazumder, Deeptankar, Sanoudou, Despina, Hajjar, Roger J., Stillitano, Francesca, Kranias, Evangelia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226909/
https://www.ncbi.nlm.nih.gov/pubmed/34204946
http://dx.doi.org/10.3390/jpm11060502

Ejemplares similares

Ejemplares similares