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Choline Kinase: An Unexpected Journey for a Precision Medicine Strategy in Human Diseases
Choline kinase (ChoK) is a cytosolic enzyme that catalyzes the phosphorylation of choline to form phosphorylcholine (PCho) in the presence of ATP and magnesium. ChoK is required for the synthesis of key membrane phospholipids and is involved in malignant transformation in a large variety of human tu...
Autores principales: | Lacal, Juan Carlos, Zimmerman, Tahl, Campos, Joaquín M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226952/ https://www.ncbi.nlm.nih.gov/pubmed/34070409 http://dx.doi.org/10.3390/pharmaceutics13060788 |
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