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Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products

Aspartame is a sweetener introduced to replace the commonly used sucrose. It was discovered by James M. Schlatter in 1965. Being 180–200 times sweeter than sucrose, its intake was expected to reduce obesity rates in developing countries and help those struggling with diabetes. It is mainly used as a...

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Autores principales: Czarnecka, Kamila, Pilarz, Aleksandra, Rogut, Aleksandra, Maj, Patryk, Szymańska, Joanna, Olejnik, Łukasz, Szymański, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227014/
https://www.ncbi.nlm.nih.gov/pubmed/34200310
http://dx.doi.org/10.3390/nu13061957
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author Czarnecka, Kamila
Pilarz, Aleksandra
Rogut, Aleksandra
Maj, Patryk
Szymańska, Joanna
Olejnik, Łukasz
Szymański, Paweł
author_facet Czarnecka, Kamila
Pilarz, Aleksandra
Rogut, Aleksandra
Maj, Patryk
Szymańska, Joanna
Olejnik, Łukasz
Szymański, Paweł
author_sort Czarnecka, Kamila
collection PubMed
description Aspartame is a sweetener introduced to replace the commonly used sucrose. It was discovered by James M. Schlatter in 1965. Being 180–200 times sweeter than sucrose, its intake was expected to reduce obesity rates in developing countries and help those struggling with diabetes. It is mainly used as a sweetener for soft drinks, confectionery, and medicines. Despite its widespread use, its safety remains controversial. This narrative review investigates the existing literature on the use of aspartame and its possible effects on the human body to refine current knowledge. Taking to account that aspartame is a widely used artificial sweetener, it seems appropriate to continue research on safety. Studies mentioned in this article have produced very interesting results overall, the current review highlights the social problem of providing visible and detailed information about the presence of aspartame in products. The studies involving the impact of aspartame on obesity, diabetes mellitus, children and fetus, autism, neurodegeneration, phenylketonuria, allergies and skin problems, its cancer properties and its genotoxicity were analyzed. Further research should be conducted to ensure clear information about the impact of aspartame on health.
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spelling pubmed-82270142021-06-26 Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products Czarnecka, Kamila Pilarz, Aleksandra Rogut, Aleksandra Maj, Patryk Szymańska, Joanna Olejnik, Łukasz Szymański, Paweł Nutrients Review Aspartame is a sweetener introduced to replace the commonly used sucrose. It was discovered by James M. Schlatter in 1965. Being 180–200 times sweeter than sucrose, its intake was expected to reduce obesity rates in developing countries and help those struggling with diabetes. It is mainly used as a sweetener for soft drinks, confectionery, and medicines. Despite its widespread use, its safety remains controversial. This narrative review investigates the existing literature on the use of aspartame and its possible effects on the human body to refine current knowledge. Taking to account that aspartame is a widely used artificial sweetener, it seems appropriate to continue research on safety. Studies mentioned in this article have produced very interesting results overall, the current review highlights the social problem of providing visible and detailed information about the presence of aspartame in products. The studies involving the impact of aspartame on obesity, diabetes mellitus, children and fetus, autism, neurodegeneration, phenylketonuria, allergies and skin problems, its cancer properties and its genotoxicity were analyzed. Further research should be conducted to ensure clear information about the impact of aspartame on health. MDPI 2021-06-07 /pmc/articles/PMC8227014/ /pubmed/34200310 http://dx.doi.org/10.3390/nu13061957 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Czarnecka, Kamila
Pilarz, Aleksandra
Rogut, Aleksandra
Maj, Patryk
Szymańska, Joanna
Olejnik, Łukasz
Szymański, Paweł
Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products
title Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products
title_full Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products
title_fullStr Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products
title_full_unstemmed Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products
title_short Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products
title_sort aspartame—true or false? narrative review of safety analysis of general use in products
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227014/
https://www.ncbi.nlm.nih.gov/pubmed/34200310
http://dx.doi.org/10.3390/nu13061957
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