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Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products
Aspartame is a sweetener introduced to replace the commonly used sucrose. It was discovered by James M. Schlatter in 1965. Being 180–200 times sweeter than sucrose, its intake was expected to reduce obesity rates in developing countries and help those struggling with diabetes. It is mainly used as a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227014/ https://www.ncbi.nlm.nih.gov/pubmed/34200310 http://dx.doi.org/10.3390/nu13061957 |
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author | Czarnecka, Kamila Pilarz, Aleksandra Rogut, Aleksandra Maj, Patryk Szymańska, Joanna Olejnik, Łukasz Szymański, Paweł |
author_facet | Czarnecka, Kamila Pilarz, Aleksandra Rogut, Aleksandra Maj, Patryk Szymańska, Joanna Olejnik, Łukasz Szymański, Paweł |
author_sort | Czarnecka, Kamila |
collection | PubMed |
description | Aspartame is a sweetener introduced to replace the commonly used sucrose. It was discovered by James M. Schlatter in 1965. Being 180–200 times sweeter than sucrose, its intake was expected to reduce obesity rates in developing countries and help those struggling with diabetes. It is mainly used as a sweetener for soft drinks, confectionery, and medicines. Despite its widespread use, its safety remains controversial. This narrative review investigates the existing literature on the use of aspartame and its possible effects on the human body to refine current knowledge. Taking to account that aspartame is a widely used artificial sweetener, it seems appropriate to continue research on safety. Studies mentioned in this article have produced very interesting results overall, the current review highlights the social problem of providing visible and detailed information about the presence of aspartame in products. The studies involving the impact of aspartame on obesity, diabetes mellitus, children and fetus, autism, neurodegeneration, phenylketonuria, allergies and skin problems, its cancer properties and its genotoxicity were analyzed. Further research should be conducted to ensure clear information about the impact of aspartame on health. |
format | Online Article Text |
id | pubmed-8227014 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-82270142021-06-26 Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products Czarnecka, Kamila Pilarz, Aleksandra Rogut, Aleksandra Maj, Patryk Szymańska, Joanna Olejnik, Łukasz Szymański, Paweł Nutrients Review Aspartame is a sweetener introduced to replace the commonly used sucrose. It was discovered by James M. Schlatter in 1965. Being 180–200 times sweeter than sucrose, its intake was expected to reduce obesity rates in developing countries and help those struggling with diabetes. It is mainly used as a sweetener for soft drinks, confectionery, and medicines. Despite its widespread use, its safety remains controversial. This narrative review investigates the existing literature on the use of aspartame and its possible effects on the human body to refine current knowledge. Taking to account that aspartame is a widely used artificial sweetener, it seems appropriate to continue research on safety. Studies mentioned in this article have produced very interesting results overall, the current review highlights the social problem of providing visible and detailed information about the presence of aspartame in products. The studies involving the impact of aspartame on obesity, diabetes mellitus, children and fetus, autism, neurodegeneration, phenylketonuria, allergies and skin problems, its cancer properties and its genotoxicity were analyzed. Further research should be conducted to ensure clear information about the impact of aspartame on health. MDPI 2021-06-07 /pmc/articles/PMC8227014/ /pubmed/34200310 http://dx.doi.org/10.3390/nu13061957 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Czarnecka, Kamila Pilarz, Aleksandra Rogut, Aleksandra Maj, Patryk Szymańska, Joanna Olejnik, Łukasz Szymański, Paweł Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products |
title | Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products |
title_full | Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products |
title_fullStr | Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products |
title_full_unstemmed | Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products |
title_short | Aspartame—True or False? Narrative Review of Safety Analysis of General Use in Products |
title_sort | aspartame—true or false? narrative review of safety analysis of general use in products |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227014/ https://www.ncbi.nlm.nih.gov/pubmed/34200310 http://dx.doi.org/10.3390/nu13061957 |
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