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Enhanced Cytotoxic Effect of Doxorubicin Conjugated to Glutathione-Stabilized Gold Nanoparticles in Canine Osteosarcoma—In Vitro Studies

Osteosarcoma (OSA) is the most common malignant bone neoplasia in humans and dogs. In dogs, treatment consists of surgery in combination with chemotherapy (mostly carboplatin and/or doxorubicin (Dox)). Chemotherapy is often rendered ineffective by multidrug resistance. Previous studies have revealed...

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Detalles Bibliográficos
Autores principales: Małek, Anna, Taciak, Bartłomiej, Sobczak, Katarzyna, Grzelak, Agnieszka, Wójcik, Michał, Mieczkowski, Józef, Lechowski, Roman, Zabielska-Koczywąs, Katarzyna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227216/
https://www.ncbi.nlm.nih.gov/pubmed/34201296
http://dx.doi.org/10.3390/molecules26123487