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Targeting the Copper Transport System to Improve Treatment Efficacies of Platinum-Containing Drugs in Cancer Chemotherapy

The platinum (Pt)-containing antitumor drugs including cisplatin (cis-diamminedichloroplatinum II, cDDP), carboplatin, and oxaliplatin, have been the mainstay of cancer chemotherapy. These drugs are effective in treating many human malignancies. The major cell-killing target of Pt drugs is DNA. Rece...

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Detalles Bibliográficos
Autores principales: Kuo, Macus Tien, Huang, Yu-Fang, Chou, Cheng-Yang, Chen, Helen H. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227247/
https://www.ncbi.nlm.nih.gov/pubmed/34201235
http://dx.doi.org/10.3390/ph14060549